Methylprednisolone

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Hypokalaemia: case report A 66-year-old woman developed hypokalaemia during treatment with methylprednisolone for idiopathic thrombocytopenic purpura (ITP). The woman was admitted to the hospital due to idiopathic thrombocytopenic purpura. She also had hypertension. On the 1st day of admission, laboratory investigations revealed a low level of thrombocytes and a low level of potassium (3.1 mEq/L). She received methylprednisolone injection 125mg three times daily along with other concomitant drugs. On day 2, the dosage of methylprednisolone was reduced to 125mg twice daily. On day 3, the dosage of methylprednisolone was reduced to 125mg once daily. On day 4, methylprednisolone dosage form was changed from injection to oral [dosage of oral formulation not stated]. After 8 care days at the hospital, she developed malaise and fatigue. She was then diagnosed with hypokalaemia (potassium level 2.3 mEq/L). Consequently, the woman received treatment with potassium for potassium correction. Three days later, her potassium level normalised (i.e. potassium level 3.9 mEq/L). Arrang ST, et al. Methylprednisolone induced hypokalemia in an Idiopathic Thrombocytopenic Purpura (ITP) patient. International Journal of Pharmacy and Pharmaceutical 803501345 Sciences 12: 83-85, No. 7, 2020. Available from: URL: http://doi.org/10.22159/ijpps.2020v12i7.37905

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