Molecular Imaging in Oncology
This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to sta
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Otmar Schober Fabian Kiessling Jürgen Debus Editors
Molecular Imaging in Oncology Second Edition
Recent Results in Cancer Research Volume 216 Series Editors Alwin Krämer, German Cancer Research Center, Heidelberg, Germany Jiade J. Lu, Shanghai Proton and Heavy Ion Center, Shanghai, China
More information about this series at http://www.springer.com/series/392
Otmar Schober • Fabian Kiessling Jürgen Debus Editors
Molecular Imaging in Oncology Second Edition
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Editors Otmar Schober Department of Nuclear Medicine University of Münster Münster, Germany Jürgen Debus Department of Radiation Oncology Ruprecht Karl University Heidelberg, Germany
Fabian Kiessling Institute for Experimental Molecular Imaging University Hospital, RWTH Aachen University Aachen, Germany
ISSN 0080-0015 ISSN 2197-6767 (electronic) Recent Results in Cancer Research ISBN 978-3-030-42617-0 ISBN 978-3-030-42618-7 (eBook) https://doi.org/10.1007/978-3-030-42618-7 1st edition: © Springer-Verlag Berlin Heidelberg 2013 2nd edition: © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
What does “molecular imaging” mean? There are several definitions in the literature. The term “molecular imaging” was formed in the early twenty-first century as a discipline at the intersection of molecular biology and in vivo imaging. It is defined as the visualization, characterization, and quantification of biologic processes at the cellular and molecular levels in living organisms. With the help of molecular imaging, cellular and molecular pathways and mechanisms of disease can be studied longitudinally in their own physiologically authentic environment in order to elucidate their molecular abnor
