Molecular Oncology: Underlying Mechanisms and Translational Advancements
Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influenc
- PDF / 5,786,893 Bytes
- 302 Pages / 439.42 x 683.15 pts Page_size
- 79 Downloads / 210 Views
olecular Oncology: Underlying Mechanisms and Translational Advancements
Molecular Oncology: Underlying Mechanisms and Translational Advancements
Ammad Ahmad Farooqi • Muhammad Ismail Editors
Molecular Oncology: Underlying Mechanisms and Translational Advancements
Editors Ammad Ahmad Farooqi Institute of Biomedical and Genetic Engineering (IBGE) Islamabad, Pakistan
Muhammad Ismail Institute of Biomedical and Genetic Engineering (IBGE) Islamabad, Pakistan
ISBN 978-3-319-53081-9 ISBN 978-3-319-53082-6 (eBook) DOI 10.1007/978-3-319-53082-6 Library of Congress Control Number: 2017934477 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Cancer is a multifaceted and genomically complex disease and intriguingly not an unfamiliar term for clinicians over centuries. Earliest evidence of cancer was discovered in human mummies and Egyptian hieroglyphs (ancient manuscripts). Certain hints have emerged pinpointing towards the presence of tumors in fossilized bones in ancient Egypt era. Biologists and archaeological researchers have collaboratively unraveled different mysteries and collected clues of bone cancer (osteosarcoma) in mummies. Egyptian history is unique in the sense that it opened new horizons for clinicians because oldest cancer description was discovered in Egypt (even though the term “cancer” was not coined) and dates back to about 3000 BC. The Edwin Smith Papyrus is doubtlessly the oldest known document on the surgery of trauma. It contained descriptions of eight cases of ulcers or tumors of the breast that were removed by cauterization technique. “Fire drill” was used as a tool
Data Loading...
