Molecular Imaging in Oncology
The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing significantly. The process of molecular imaging includes key biotarget identification, design of specific molecular imaging probes, and their preclinical eval
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Otmar Schober Burkhard Riemann •
Editors
Molecular Imaging in Oncology
123
Editors Otmar Schober Klinik für Nuklearmedizin Universitätsklinikum Münster Münster Germany
ISSN 0080-0015 ISBN 978-3-642-10852-5 DOI 10.1007/978-3-642-10853-2
Burkhard Riemann Klinik für Nuklearmedizin Universitätsklinikum Münster Münster Germany
ISBN 978-3-642-10853-2
(eBook)
Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2012942712 Springer-Verlag Berlin Heidelberg 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
What does ‘‘molecular imaging’’ mean? There are several definitions in the literature. The term ‘‘molecular imaging’’ was formed in the early twenty-first century as a discipline at the intersection of molecular biology and in vivo imaging. It is defined as the visualization, characterization, and quantification of biologic processes at the cellular and molecular levels in living organisms. With the help of molecular imaging procedures cellular and molecular pathways and mechanisms of disease can be studied in their own physiologically authentic environment in order to reveal their molecular abnormalities that form the basis of disease. This is a really innovative
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