Pacing and Defibrillation
Pacing and defibrillation systems monitor and treat inappropriate cardiac rhythms. In general, these inappropriate rhythms result in cardiac outputs that are inadequate to meet metabolic demands, and thus can be life-threatening. In order to best understa
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Timothy G. Laske, Anna Legreid Dopp, Michael D. Eggen, and Paul A. Iaizzo
Abstract
Pacing and defibrillation systems monitor and treat inappropriate cardiac rhythms. In general, these inappropriate rhythms result in cardiac outputs that are inadequate to meet metabolic demands, and thus can be life-threatening. In order to best understand the function of such pacing and defibrillation systems, the underlying physiologic situations indicated for their use must also be defined and understood. Furthermore, as with the design of any biomedical device or system, a first principles understanding of the appropriate physiologic behavior is a prerequisite to the definition of the performance characteristics of the device. This chapter primarily aims to provide a basic understanding of the physiologic conditions that require intervention with pacing and/or defibrillation systems, as well as introduce technical information about these systems to provide the reader with a foundation for future research and reading on this topic. Keywords
Cardiac pacing • Defibrillation • Cardiac arrhythmia • Electrical stimulation • Antiarrhythmic drugs • Drug interactions • Implantable pulse generator • Implantable cardioverter defibrillator • Leadless pacemaker
Electronic supplementary material The online version of this chapter (doi:10.1007/978-3-319-19464-6_30) contains supplementary material, which is available to authorized users. T.G. Laske, PhD (*) Department of Surgery, University of Minnesota, Minneapolis, MN, USA Medtronic plc, 8200 Coral Sea Street NE, MVS 46, Minneapolis, MN 55112, USA Pharmacy Society of Wisconsin, Madison, WI, USA e-mail: [email protected] A.L. Dopp, PharmD Pharmacy Society of Wisconsin, Madison, WI, USA M.D. Eggen, PhD Department of Surgery, University of Minnesota, Minneapolis, MN, USA Medtronic plc, 8200 Coral Sea Street NE, MVS 46, Minneapolis, MN 55112, USA P.A. Iaizzo, PhD Department of Surgery, University of Minnesota, Minneapolis, MN, USA
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Introduction
Pacing and defibrillation systems both monitor and treat inappropriate cardiac rhythms. In general, these inappropriate rhythms result in cardiac outputs that are inadequate to meet metabolic demands, and thus can be life-threatening. Currently, over 600,000 Americans have pacemakers and 150,000 have implantable cardioverter defibrillators (ICDs) [1]. In order to best understand the function of such pacing and defibrillation systems, the underlying physiologic situations indicated for their use must also be defined and understood. Furthermore, as with the design of any biomedical device or system, a first principles understanding of the appropriate physiologic behavior is a prerequisite to the definition of the performance characteristics of the device. This chapter primarily aims to provide a basic understanding of the physiologic conditions that require intervention with
© Springer International Publishing Switzerland 2015 P.A. Iaizzo (ed.), Handbook of Cardiac Anatomy, Physiology, and Devices, DOI 10.1007/978-3-319-19464-6_30
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