Particles and Nanoparticles in Pharmaceutical Products Design, Manuf
This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The b
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Henk G. Merkus Gabriel M. H. Meesters Wim Oostra Editors
Particles and Nanoparticles in Pharmaceutical Products Design, Manufacturing, Behavior and Performance
AAPS Advances in the Pharmaceutical Sciences Series Volume 29
Series Editor Yvonne Perrie, Strathclyde Institute of Pharmacy, University of Strathclyde, Bearsden, Dunbartonshire, UK
The AAPS Advances in the Pharmaceutical Sciences Series, published in partnership with the American Association of Pharmaceutical Scientists, is designed to deliver volumes authored by opinion leaders and authorities from around the globe, addressing innovations in drug research and development, and best practice for scientists and industry professionals in the pharma and biotech industries.
More information about this series at http://www.springer.com/series/8825
Henk G. Merkus Gabriel M. H. Meesters Wim Oostra •
Editors
Particles and Nanoparticles in Pharmaceutical Products Design, Manufacturing, Behavior and Performance
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Editors Henk G. Merkus Pijnacker, Zuid-Holland The Netherlands
Wim Oostra Hilversum, Noord-Holland The Netherlands
Gabriel M. H. Meesters Delft, Zuid-Holland The Netherlands
ISSN 2210-7371 ISSN 2210-738X (electronic) AAPS Advances in the Pharmaceutical Sciences Series ISBN 978-3-319-94173-8 ISBN 978-3-319-94174-5 (eBook) https://doi.org/10.1007/978-3-319-94174-5 Library of Congress Control Number: 2018947793 © American Association of Pharmaceutical Scientists 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Pharmaceutical products occur in a wide variety of formulations, viz. powders, tablets, capsules, liposomes, extended-release formulations, crèmes, ointments, nanomedicines, coatings and theranostic partic
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