Patient-Derived Xenograft Models of Human Cancer
This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available e
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Yuzhuo Wang Dong Lin Peter W. Gout Editors
Patient-Derived Xenograft Models of Human Cancer
Molecular and Translational Medicine Series editors William B. Coleman Dept of Pathology and Lab Medicine Univ of N.Carolina School of Medicine Chapel Hill, North Carolina USA Gregory J. Tsongalis Dept of Pathology and Lab Medicine Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire USA
As we enter into this new era of molecular medicine with an expanding body of knowledge related to the molecular pathogenesis of human disease and an increasing recognition of the practical implications for improved diagnostics and treatment, there is a need for new resources to inform basic scientists and clinical practitioners of the emerging concepts, useful applications, and continuing challenges related to molecular medicine and personalized treatment of complex human diseases. This series of resource/reference books entitled Molecular and Translational Medicine is primarily concerned with the molecular pathogenesis of major human diseases and disease processes, presented in the context of molecular pathology, with implications for translational molecular medicine and personalized patient care. More information about this series at http://www.springer.com/series/8176
Yuzhuo Wang • Dong Lin • Peter W. Gout Editors
Patient-Derived Xenograft Models of Human Cancer
Editors Yuzhuo Wang Department of Urologic Sciences University of British Columbia Vancouver, BC, Canada Department of Experimental Therapeutics BC Cancer Research Centre Vancouver, BC, Canada Vancouver Prostate Centre Vancouver, BC, Canada
Peter W. Gout Department of Experimental Therapeutics BC Cancer Research Centre Vancouver, BC, Canada Living Tumor Laboratory BC Cancer Agency/Vancouver Prostate Centre Vancouver, BC, Canada
Dong Lin Department of Urologic Sciences University of British Columbia Vancouver, BC, Canada Department of Experimental Therapeutics BC Cancer Research Centre Vancouver, BC, Canada Vancouver Prostate Centre Vancouver, BC, Canada
ISSN 2197-7852 ISSN 2197-7860 (electronic) Molecular and Translational Medicine ISBN 978-3-319-55824-0 ISBN 978-3-319-55825-7 (eBook) DOI 10.1007/978-3-319-55825-7 Library of Congress Control Number: 2017943865 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the aut
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