Personal exposure to PM 2.5 -bound heavy metals associated with cardiopulmonary function in general population
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RESEARCH ARTICLE
Personal exposure to PM2.5-bound heavy metals associated with cardiopulmonary function in general population Peiwei Xu 1 & Xiaoqing He 2 & Shengliang He 1 & Jinbin Luo 2 & Qiang Chen 2 & Zuoyi Wang 2 & Aihong Wang 3 & Beibei Lu 3 & Lizhi Wu 1 & Yuan Chen 1 & Dandan Xu 1 & Weizhong Chen 1 & Zhijian Chen 1 & Xiaofeng Wang 1 & Xiaoming Lou 1 Received: 19 April 2020 / Accepted: 28 September 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract To better understand the cardiopulmonary alterations associated with personal exposed PM2.5-bound heavy meals, we conducted a cross-sectional study in 2018 on 54 general residents. For each subject, PM2.5 exposure filter was collected by a low-volume sampler for 24 h; blood and urine samples were collected subsequently. Heavy metals in PM2.5, blood, and urine samples were determined by inductively coupled plasma mass spectrometry method. PM2.5-bound Mn, Cd, Sb, Pb, and Ni levels were 20.5, 9.27, 9.59, 28.3, and 16.9 ng/m3, respectively. The distribution of these metals followed the order: Pb (33.47%) > Mn (24.24%) > Ni (19.99%) > Sb (11.34%) > Cd (10.96%). The distribution of heavy meals in PM2.5, blood, and urine differed from each other. PM2.5-bound Cd, Pb levels were positively correlated with blood Cd, Pb levels (r = 0.323, r = 0.334, p < 0.05), respectively. PM2.5-bound Cd level was significantly higher in smoking group than non-smoking group (28.8 vs. 7.27 ng/m3, p < 0.01), same as Sb level (12.0 vs. 9.34 ng/m3, p < 0.01). Cd and Pb exposure might interact with cardiovascular function through autonomic regulation. No significant correlation was observed between metal exposure and pulmonary function. In conclusion, our data suggested that personal exposure to specific PM2.5-bound heavy metals might interact with profound cardiovascular alterations. Keywords PM2.5 . Personal exposure . Heavy metal . Cardiovascular . Pulmonary
Introduction Air pollution has been a public health concern for decades. The World Health Organization (WHO) declared that three million global deaths were attributable to ambient air pollution in 2012; about 87% occurred in low- and middle-income countries (World Health Organization 2016). As a fastXiaoqing He is Co-first author Responsible Editor: Lotfi Aleya Electronic supplementary material The online version of this article (https://doi.org/10.1007/s11356-020-11034-1) contains supplementary material, which is available to authorized users. * Xiaoming Lou [email protected] 1
Zhejiang Provincial Center for Disease Control and Prevention, 3399 Bin Sheng Road, Binjiang District, Hangzhou 310051, China
2
Jinhua Center for Disease Control and Prevention, Jinou Road 1366, Jinhua 321002, China
3
Ningbo Center for Disease Control and Prevention, Yongfeng Road 237, Ningbo 315010, China
developing country, China has made great efforts in controlling air pollution. Still, ambient particulate matter pollution ranked the fourth leading risk factor at the national level for deaths and disability-adjusted life-years in C
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