Pre-dialysis serum creatinine as an independent predictor of responsiveness to zinc supplementation among patients on he
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ORIGINAL ARTICLE
Pre‑dialysis serum creatinine as an independent predictor of responsiveness to zinc supplementation among patients on hemodialysis Teppei Okamoto1,2 · Shingo Hatakeyama2 · Kyo Togashi2 · Tomoko Hamaya2 · Yoshimi Tanaka1,2 · Kengo Imanishi1 · Tooru Takashima1 · Fumitada Saitoh1 · Tadashi Suzuki3 · Chikara Ohyama2 Received: 13 January 2020 / Accepted: 1 June 2020 © Japanese Society of Nephrology 2020
Abstract Background To investigate whether pre-dialysis level of serum creatinine (SCre) could indicate the responsiveness to zinc supplementation of patients on maintenance hemodialysis (MHD). Methods We retrospectively reviewed the results of our previous randomized study of 91 patients who had been on MHD and received zinc supplementation with either zinc acetate hydrate (ZAH; zinc, 50 mg/day) or polaprezinc (PPZ; zinc, 34 mg/day). A late response to zinc supplementation was defined as a serum zinc level of
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