Pregnancy Outcome in Women with Polycystic Ovary Syndrome
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ORIGINAL ARTICLE
Pregnancy Outcome in Women with Polycystic Ovary Syndrome Amandeep Mann1 · Haritha Sagili2 · Murali Subbaiah1 Received: 31 March 2020 / Accepted: 8 July 2020 © Federation of Obstetric & Gynecological Societies of India 2020
Abstract Background/Purpose Pregnant women with polycystic ovary syndrome seem to be prone for adverse maternal and perinatal outcomes, but there is no conclusive evidence. Indian data evaluating the pregnancy outcome in women with polycystic ovary syndrome are sparse. This study was proposed to evaluate the pregnancy outcome in women with polycystic ovary syndrome. Methods This descriptive study on 135 pregnant women with polycystic ovary syndrome was carried out in a tertiary care hospital in South India from January 2016 to October 2017. Data regarding present pregnancy, polycystic ovary syndrome and maternal/ perinatal outcomes were analysed using SPSS version 20. Categorical variables studied were parity, various maternal and perinatal outcomes. Results The mean age was 26.8 years, 77% had high BMI, and 88% had history of primary infertility. The mean age was 26.8 years, 77% had high BMI, and 88% had history of primary infertility. The proportion of hypertensive disorders of pregnancy was (17.8%), PROM (18.5%), low APGAR score at 5 min (13%), gestational diabetes (13%), miscarriage (2.2%), preterm delivery (10.4%), caesarean delivery (30.4%), low birth weight babies (2%), macrosomia (0.7%), PPROM (8%), perinatal mortality (2%) and NICU admission (20%). Conclusion The proportion of hypertensive disorders of pregnancy, PROM, low birth weight babies, low APGAR score at 5 min was found to be higher, but the proportion of GDM, miscarriage, preterm delivery, meconium stained liquor, caesarean delivery, small for gestational age/IUGR, macrosomia, PPROM, perinatal mortality, NICU admission and congenital anomalies was found to be either similar or lower in pregnant women with PCOS in our study to those described in the general pregnant population. Keywords PCOS · Pregnancy outcome · Maternal outcome · Perinatal outcome
Introduction Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. It is estimated that 6 to 15% of women suffer from this disease [1],
Dr. Amandeep Mann, MS in Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India. Dr. Haritha Sagili, MD, MRCOG, MFSRH, Additional Professor in Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India. Dr. Murali Subbaiah, MS, Associate Professor in Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India. * Haritha Sagili [email protected] 1
Department of Obstetrics and Gynaecology, JIPMER, Puducherry 605006, India
Department of Obstetrics and Gynaecology, JIPMER, Puducherry 605005, India
2
diagnosed by any two of the following three criteria: menstrual irregularity with oligo-anovulation, hyperandrogenism and polycystic ovarian features on ultrasound [2]. Pregnant women with PCOS seem to be prone for adverse maternal and peri
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