Prevalence of and risk factors for anxiety and depression in Chinese patients with unruptured intracranial aneurysms tre
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RESEARCH ARTICLE
Open Access
Prevalence of and risk factors for anxiety and depression in Chinese patients with unruptured intracranial aneurysms treated by endovascular intervention Xiao-Dong Zhai1,2, Jia-Xing Yu1,2, Yong-Jie Ma1,2, Si-Shi Xiang1,2, Gui-Lin Li1,2, Chuan He1,2, Peng Hu1,2 and Hong-Qi Zhang1,2*
Abstract Background: Studies on anxiety and depression in unruptured intracranial aneurysm (UIA) patients after treatment via endovascular intervention are rare and controversial. We aimed to explore the prevalence of anxiety and depression among Chinese patients with UIAs treated by endovascular intervention and to identify which factors contribute to the development of these symptoms. Methods: We performed a cross-sectional study on anxiety and depression in patients who underwent endovascular treatment for UIAs using the Hospital Anxiety and Depression Scale (HADS). The demographic, clinical and radiological data for all patients were retrospectively collected from the aneurysm database and medical records. Moreover, we utilized data from a large sample of 200 UIA patients and multivariate logistic regression analysis to investigate the risk factors for anxiety and depression in these patients. Candidate variables with P values less than 0.20 in univariate analysis were included in the multivariate logistic regression analysis. Results: Two hundred patients returned completed questionnaires in this study. Of these 200 patients, 34 (17.0%) suffered from anxiety and 31 (15.5%) suffered from depression 30.67 ± 8.6 months after being discharged. The multivariate analysis results indicated that shorter sleep times were statistically significantly associated with depression (OR = 1.62, 95% CI: 1.14 ~ 2.29, P = 0.007, Adjusted P = 0.02). . (Continued on next page)
* Correspondence: [email protected] 1 Department of Neurosurgery, Xuanwu Hospital, No. 45 Changchun Street, Xicheng District, Beijing, China 2 China International Neuroscience Institute (China-INI), Beijing, China
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