Primary Central Nervous System Tumors Pathogenesis and Therapy
This comprehensive, yet practical, text is a ready collection of the most up-to-date information on primary CNS tumors. Authored by a carefully selected group of the world’s leading clinicians and scientists, the book is divided into three sections. The o
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Current Clinical Oncology Maurie Markman, MD, SERIES EDITOR
For other titles published in this series, go to http://www.springer.com/series/7631
Primary Central Nervous System Tumors Pathogenesis and Therapy Edited by
Andrew D. Norden, MD, MPH Brigham and Women’s Hospital Dana-Farber Cancer Institute Harvard Medical School Boston, MA USA
David A. Reardon, MD Duke University Medical Center The Preston Robert Tisch Brain Tumor Center at Duke Durham, NC USA
Patrick Y.C. Wen, MD Brigham and Women’s Hospital Dana-Farber Cancer Institute Harvard Medical School Boston, MA USA
Editors Andrew D. Norden, MD, MPH Division of Neuro-Oncology Department of Neurology Brigham and Women’s Hospital Center for Neuro-Oncology Dana-Farber Cancer Institute Harvard Medical School Boston, MA USA
David A. Reardon, MD Departments of Surgery and Pediatrics Duke University Medical Center The Preston Robert Tisch Brain Tumor Center at Duke Durham, NC USA
Patrick Y.C. Wen, MD Division of Neuro-Oncology Department of Neurology Brigham and Women’s Hospital Center for Neuro-Oncology Dana-Farber Cancer Institute Harvard Medical School Boston, MA USA
ISBN 978-1-60761-165-3 e-ISBN 978-1-60761-166-0 DOI 10.1007/978-1-60761-166-0 Springer New York Dordrecht Heidelberg London © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Preface
In preparing Primary Central Nervous System Tumors: Pathogenesis and Therapy, we set out to write a textbook that would be comprehensive yet accessible. We wanted readers to have access to the cutting-edge advances in molecular biology and genomics that are revolutionizing neuro-oncology; at the same time, we required that our authors provide practical clinical information that is needed to make intelligent therapeutic decisions. As you will see, we recruited some of the most accomplished neurologists, oncologists, cancer scientists, and nu
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