Aging and Lung Disease A Clinical Guide

People age 65 and older are the fastest growing segment of the U.S. population.  In the 2010 census 16% of the population, 50 million people, were age 65 and older.  That number is projected to increase to 66 million by the year 2050.  Life

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Margaret Pisani Editor

Aging and Lung Disease A Clinical Guide

Editor Margaret Pisani, MD, MPH Associate Professor Yale University School of Medicine New Haven, CT, USA [email protected]

ISBN 978-1-60761-726-6 e-ISBN 978-1-60761-727-3 DOI 10.1007/978-1-60761-727-3 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011937963 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)

Preface

People age 65 and older are the fastest growing segment of the US population. In the 2010 census, 16% of the population, 50 million people, were age 65 and older. That number is projected to increase to 66 million by the year 2050. Compared to the 2000 census the population aged 65 and older grew at a rate of 15.1%. Life expectancy has also increased, with recent CDC reports indicating life expectancy at 77.9 years. Age-adjusted death rates have decreased significantly with the largest changes occurring in older patients. Despite these trends, the ten leading causes of death include several pulmonary etiologies including lung cancer, chronic respiratory diseases, influenza, and pneumonia. This volume on aging and pulmonary disease is devoted to understanding the impact of respiratory diseases in older patients. It includes reviews of physiology of the aging lung, allergy and immunology of aging, as well as sleep changes over the life cycle. There are also comprehensive reviews on specific disease topics including chronic obstructive pulmonary disease, lung cancer, atypical mycobacteria, interstitial lung disease, pulmonary hypertension, pulmonary embolism, obstructive sleep apnea, and sleep disorders in older patients. Two chapters focus on unique issues in older patients: HIV and lung transplant. Included also are important chapters on asse