Alcoholic and Non-Alcoholic Fatty Liver Disease Bench to Bedside
This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and non-alcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk fact
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Alcoholic and Non-Alcoholic Fatty Liver Disease
Naga Chalasani • Gyongyi Szabo Editors
Alcoholic and Non-Alcoholic Fatty Liver Disease Bench to Bedside
Editors Naga Chalasani, M.D. Division of Gastroenterology and Hepatology Indiana University School of Medicine Indianapolis, IN, USA
Gyongyi Szabo, M.D., Ph.D. Department of Medicine University of Massachusetts Medical School Worcester, MA, USA
ISBN 978-3-319-20537-3 ISBN 978-3-319-20538-0 DOI 10.1007/978-3-319-20538-0
(eBook)
Library of Congress Control Number: 2015958158 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
To my parents, Sujani and C.N. Rao, for their big dreams and sacrifices, and to my brother, Prasad, who is always there for me; To my wife, Satya, and to our son, Sai, who are the joy of my life; To my namesake, DWC, who is behind most of my major professional milestones. Naga Chalasani To my family, mentors, and friends. Gyongyi Szabo
Preface
Alcoholic liver disease (ALD) and Nonalcoholic fatty liver disease (NAFLD) are among the most common causes of cirrhosis, liver failure, and liver cancer worldwide. Histologically, they resemble each other and they both share several common pathogenetic mechanisms. Over the last decade, steady progress has been made in almost all aspects of these two diseases, and this book reflects our attempt to integrate these new developments into existing disease pathogenesis and management paradigms. This book is developed as a state-of-theart resource for medical students, clinicians, pathologists, clinical researchers, basic science investigators, and pharmaceutical industry worldwide. At the outset, we believed that a single book that includes both ALD and NAFLD would be highly desirable for various stakeholders, but orga
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