An Analysis of Medication Prescriptions for Hypertension in Urban and Rural Residents in Tianjin

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ORIGINAL RESEARCH

An Analysis of Medication Prescriptions for Hypertension in Urban and Rural Residents in Tianjin Yingyi Zhang . Hua Yang . Ruiying Wang . Fumei Zhao . Ting Liu . Ying Zhang . Zhigang Guo . Hongliang Cong

Received: July 16, 2020 Ó Springer Healthcare Ltd., part of Springer Nature 2020

ABSTRACT Introduction: This study aims to examine the medication prescriptions for hypertension in Tianjin. Methods: Patients with hypertension in Tianjin were enrolled in this study. The patients’ ages ranged from 35 to 75 years. A questionnaire survey and physical examination were completed to collect clinical data. Thereafter, a statistical analysis of the medication prescriptions was conducted with different age groups and different grades of hypertension. Results: The results show that, in the total population, and for the young, middle-aged, and older groups, the proportions of single-drug use were 62.97%, 59.26%, 62.76%, and 63.49%, respectively, and the highest rate was for Yingyi Zhang and Hua Yang are co-first authors.

Digital Features This article is published with digital features to facilitate understanding of the article. You can access the digital features on the article’s associated Figshare page. To view digital features for this article go to https://doi.org/10.6084/m9.figshare.12793880. Y. Zhang  H. Yang  R. Wang  Z. Guo  H. Cong (&) Department of Cardiology, Tianjin Chest Hospital, Tianjin 300222, China e-mail: [email protected] F. Zhao  T. Liu  Y. Zhang Tianjin Cardiovascular Institute, Tianjin 300222, China

calcium channel blocker (CCB) use. The rates of the two drug classes were 24.51%, 29.63%, 25.13%, and 23.15%, respectively. The drug use rate of CCBs combined with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor antagonists (ARBs) was the highest. The rates of the three drug classes were 4.08%, 4.94%, 4.36%, and 3.52%, respectively, and the highest was ACEI/ARB and CCB combined with diuretics. The rates of the four drug classes were low. Regarding the hypertension grade, in grade 1, grade 2, and grade 3, the rates of single-drug use were 63.53%, 62.69%, and 58.38%, respectively. The rates of the two drug classes were 24.62%, 23.97%, and 25.05%, while the rates of the three drug classes were 3.86%, 4.39%, and 5.34%, respectively. Conclusion: The rate of single-drug use was high, and the rate of combined drug use in the youth group was slightly higher than in the middle-aged and older age groups. The combination of two drugs was common. In grades 2 and 3 hypertension, the rate of combined drug use remained low. Keywords: Angiotensin-converting enzyme inhibitor; Angiotensin receptor antagonist; Hypertension; Medication prescription; Physiological characteristics

Adv Ther

Key Summary Points This study aims to examine the medication prescriptions for hypertension in Tianjin. This study is beneficial in guiding rational drug use based on understanding current conditions.

INTRODUCTION Hypertension is an international public health concern that is strongly linked