Cancer Drug Resistance Overviews and Methods
This volume discusses the latest advancements and technologies used in cancer drug resistance research. Cancer Drug Resistance: Overviews and Methods contains chapters that cover topics such as: studying the mechanics of resistance to DNA damaging th
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José Rueff António Sebastião Rodrigues Editors
Cancer Drug Resistance Overviews and Methods
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Cancer Drug Resistance Overviews and Methods
Edited by
José Rueff Centre for Toxicogenomics and Human Health, Genetics, Oncology and Human Toxicology, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal
António Sebastião Rodrigues Centre for Toxicogenomics and Human Health, Genetics, Oncology and Human Toxicology, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal
Editors José Rueff Centre for Toxicogenomics and Human Health, Genetics, Oncology and Human Toxicology NOVA Medical School/Faculdade de Ciências Médicas Universidade Nova de Lisboa Lisbon, Portugal
António Sebastião Rodrigues Centre for Toxicogenomics and Human Health, Genetics, Oncology and Human Toxicology NOVA Medical School/Faculdade de Ciências Médicas Universidade Nova de Lisboa Lisbon, Portugal
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-3345-7 ISBN 978-1-4939-3347-1 (eBook) DOI 10.1007/978-1-4939-3347-1 Library of Congress Control Number: 2016930407 Springer New York Heidelberg Dordrecht London © Springer Science+Business Media New York 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Cover Image: Immunolfluorescence with anti-P-glycoprotein/MDR-1 monoclonal antibody of Lymphoma MDR cell line (Chapter 6). Printed on acid-free paper Humana Press is a brand of Springer Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www.springer.com)
Preface The last few decades have been witness to a far-reaching transformation in the biomedical sciences in which genetics has been one amongst the main actors. Indeed, genetics c
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