CHA 2 DS 2 -VASc score as predictor of stroke and all-cause death in stable ischaemic heart disease patients without atr

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CHA2DS2‑VASc score as predictor of stroke and all‑cause death in stable ischaemic heart disease patients without atrial fibrillation Jose J. Sanchez Fernandez1 · Martín Ruiz Ortiz2 · Francisca Montoro Ballesteros1 · Cristina Ogayar Luque2 · Elías Romo Penas2 · Mónica Delgado Ortega2 · Dolores Mesa Rubio2 Received: 1 March 2020 / Revised: 23 May 2020 / Accepted: 29 May 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Background  Cerebrovascular and coronary artery disease share risk factors. The aim was to study C ­ HA2DS2-VASc score as predictor of stroke incidence and death in a sample of patients with sinus rhythm and stable ischemic heart disease (sIHD) during long-term follow-up. Methods  1184 patients with sIHD and without atrial fibrillation were included in this single-centre prospective cohort study between February 2000 and January 2004. Stroke and death prediction abilities of ­CHA2DS2-VASc score in this population were investigated. Results  The median age was 66 (interquartile range (IQR), 60–73 years). The mean follow-up was 11.2 ± 10 years (maximum 17 years). Along this period, 137 patients (11.6% of the sample) suffered a stroke. The mean value of ­CHA2DS2-VASc score was 3.04 ± 1.36, with C ­ HA2DS2-VASc score ≤ 4 in 85.5% of the sample. Higher C ­ HA2DS2-VASc score at baseline was associated with higher risk of suffering stroke (Hazard Ratio = 1.36, 95% CI 1.20–1.54, p