Characterising the orientation-specific pattern-onset visual evoked potentials in children with bilateral refractive amb
- PDF / 1,198,821 Bytes
- 15 Pages / 547.087 x 737.008 pts Page_size
- 76 Downloads / 168 Views
(0123456789().,-volV) ( 01234567 89().,-volV)
ORIGINAL RESEARCH ARTICLE
Characterising the orientation-specific pattern-onset visual evoked potentials in children with bilateral refractive amblyopia and non-amblyopic controls Tiong Peng Yap Mei Ying Boon
. Chi D. Luu . Catherine M. Suttle . Audrey Chia .
Received: 29 November 2019 / Accepted: 9 September 2020 Ó Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose An orientation-specific visual evoked potential (osVEP) protocol was developed to probe meridional anisotropies in children with refractive amblyopia. The aim was to characterise the osVEP response in children with bilateral refractive amblyopia, evaluate the intra-session repeatability of the main osVEP components (C1, C2 and C3), coefficient of repeatability (CoR) of the response to gratings in different meridians and determine if refractive amblyopes have poorer repeatability as compared with nonamblyopic controls. Methods Children aged 4–7 years with newly diagnosed and untreated bilateral refractive amblyopia and non-amblyopic controls were recruited. Orientationspecific pattern-onset VEPs were recorded in response
T. P. Yap (&) C. M. Suttle M. Y. Boon School of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia e-mail: [email protected] C. D. Luu Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC, Australia C. D. Luu Ophthalmology, Department of Surgery, The University of Melbourne, Parkville, VIC, Australia
to an achromatic sinewave grating stimulus of 4 cycles per degree under monocular and binocular stimulation. The grating lines used for monocular stimulation were parallel with the subjects’ most positive and negative astigmatic meridians when considered in sphero-minus cylinder form (Meridians 1 and 2, respectively). In subjects without astigmatism, meridians 1 and 2 were designated horizontal and vertical gratings, respectively. Binocular stimuli were presented with grating lines parallel to meridians 45, 90, 135 and 180°. The repeatability of latencies of the main osVEP components (C1, C2 and C3) were investigated using two successive osVEPs recordings for each stimulus meridian and the CoR for each component’s latencies were assessed.
A. Chia Paediatric Ophthalmology and Adult Strabismus Department, Singapore National Eye Centre (SNEC), Singapore, Singapore A. Chia Paediatric Ophthalmology and Strabismus Department, KK Women’s and Children’s Hospital (KKH), Singapore, Singapore
C. M. Suttle Division of Optometry and Visual Sciences, University of London, London, England, UK
123
Doc Ophthalmol
Results Seven amblyopic children (Visual acuity (VA) ranging from 0.08 to 0.40 LogMAR in the less amblyopic eye and 0.26–0.52 LogMAR in the more amblyopic eye) and 7 non-amblyopic controls (VA ranging from 0.00 to 0.02 LogMAR in either eye), with a median age of 4.6 and 7.0 years, respectively, completed the study. C1 had the highest CoR for most conditions assessed. Ratio of CoRs C1:C2
Data Loading...
