Chlorhexidine
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Chlorhexidine Allergic contact dermatitis to phenolsulfonphthalein excipient: case report A 28-year-old woman developed allergic contact dermatitis after application of a chlorhexidine solution; subsequent patch tests revealed a positive reaction to phenolsulfonphthalein, a component of the solution. The woman, who had a history of dermatitis following surgery, underwent ovarian cyst surgery. Chlorhexidine solution [Klorhexol] was applied for disinfection [dosage not stated]. The day after surgery, dermatitis appeared on the disinfected skin area and spread over her body. At presentation 1 week after surgery, she had dermatitis over her whole body, with a pustulopapular skin eruption on her back and abdomen. Patch testing showed positive reactions to the chlorhexidine solution and to phenolsulfonphthalein. A use test of the chlorhexidine solution, applied to her lower arm in two daily applications, showed pruritus and small papules after a few days and a positive result on day 7. [Patient outcome not stated.] Kaminska R, et al. Allergic contact dermatitis from phenolsulfonphthalein in chlorhexidine solution. Contact Dermatitis 56: 358-360, No. 6, Jun 2007 801071841 Finland
0114-9954/10/1160-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 14 Jul 2007 No. 1160
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