Clinical Research Case Studies of Successes and Failures
This book provides insights into how to be a productive clinical researcher via real-life case examples of successful clinical research -- and also clinical research gone awry. Through these examples of success and failure, the book develops a bluep
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Clinical Research Case Studies of Successes and Failures
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Clinical Research
John G. Brock-Utne
Clinical Research Case Studies of Successes and Failures
John G. Brock-Utne Professor Department of Anesthesia Stanford University Stanford, CA, USA
ISBN 978-1-4939-2515-5 ISBN 978-1-4939-2516-2 DOI 10.1007/978-1-4939-2516-2
(eBook)
Library of Congress Control Number: 2015938594 Springer New York Heidelberg Dordrecht London © Springer Science+Business Media New York 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www.springer.com)
For the next generation: Matthew B. Brock-Utne Tobias J. Brock-Utne Anders C. Brock-Utne Jasper L. Brock-Utne Stefan S. Brock-Utne Charlotte E. Brock-Utne
Preface
The intention of this book is to highlight the many pitfalls that can occur when contemplating doing clinical research. This is based on my over 45 years of involvement in clinical research in four continents. Even though some of my mishaps have occurred over 40 years ago, I can assure you that these mistakes occur even to this day with monotonous regularity. Hence the book. After each case history a question is posed. These are questions you may be faced with as a clinical researcher. The solutions suggested may be controversial and as such may form the basis for discussions on how best to proceed in your special circumstance. The object of these many stories is to alert the clinical researcher and especially the El Toro researcher that there are many potential disasters waiting to happen when you embark on clinical research. But most of all the reader will hopefully understand that meticulous planning is essential for being successful in this field. Always remember that the object is to achieve one’s research goals quickly with a minimal risk of wasting time and resources. To quote Marks (1) and to paraphrase Hippocrates of Kos (2): (1. “The success of res
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