Diagnostic Nuclear Medicine

The field of nuclear medicine is undergoing rapid expansion, and is evolving into diagnostic molecular imaging. During recent years, dual-modality imaging with PET/CT has gained acceptance and this is currently the fastest-growing technique for

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MEDICAL RADIOLOGY

Diagnostic Imaging Editors: A. L. Baert, Leuven K. Sartor, Heidelberg

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Christiaan Schiepers (Ed.)

Diagnostic Nuclear Medicine 2nd Revised Edition With Contributions by M. Allen-Auerbach · R. Barone · D. Bequé · C. P. Bleeker-Rovers · G. Bormans · R. Campisi J. Czernin · M. Dahlbom · J. J. Frost · S. S. Gambhir · G. Goerres · D. A. Hillier · C. Hoh F. Jamar · F. Y. J. Keng · G. Lucignani · H. R. Nadel · J. Nuyts · W. J. G. Oyen · H. J. J. M. Rennen H. D. Royal · H. R. Schelbert · C. Schiepers · M. L. Schipper · H. C. Steinert · M. E. Stilwell T. Traub-Weidinger · M. Tulchinsky · J.-L. C. P. Urbain · K. Verbeke · A. Verbruggen · I. Virgolini G. K. von Schulthess · S. I. Ziegler Foreword by

A. L. Baert With 142 Figures in 235 Separate Illustrations, 11 in Color and 32 Tables

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Christiaan Schiepers, MD, PhD Department of Molecular and Medical Pharmacology David Geffen School of Medicine at UCLA 10833 Le Conte Avenue, AR-144 CHS Los Angeles, CA 90095-6942 USA

Medical Radiology · Diagnostic Imaging and Radiation Oncology Series Editors: A. L. Baert · L. W. Brady · H.-P. Heilmann · M. Molls · K. Sartor Continuation of Handbuch der medizinischen Radiologie Encyclopedia of Medical Radiology

Library of Congress Control Number: 2004106812

ISBN 3-540-42309-5 Springer Berlin Heidelberg New York ISBN 978-3-540-42309-6 Springer Berlin Heidelberg New York This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is part of Springer Science+Business Media http//www.springeronline.com © Springer-Verlag Berlin Heidelberg 2006 Printed in Germany The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every case the user must check such information by consulting the relevant literature. Medical Editor: Dr. Ute Heilmann, Heidelberg Desk Editor: Ursula N. Davis, Heidelberg Production Editor: Kurt Teichmann, Mauer Cover-Design and Typesetting: Verlagsservice Teichmann, Mauer Printed on acid-free paper – 21/3151xq – 5 4 3 2 1 0

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Foreword

Since the publication of the first edition of “Diagnostic Nuclear Medicine” rapid progress has occurred in the field of nuclear medicine imaging. Multimodality imaging, image