Factors associated with the poor outcomes in diabetic patients with COVID-19
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RESEARCH ARTICLE
Factors associated with the poor outcomes in diabetic patients with COVID-19 Hadith Rastad 1 & Hanieh-Sadat Ejtahed 2,3 & Armita Mahdavi-Ghorabi 4 & Masoud Arzaghi 5 & Anis Safari 6 & Ehsan Shahrestanaki 6 & Mohammad Rezaei 7 & Mohammad Mahdi Niksima 7 & Akram Zakani 8 & Seyede Hanieh Dehghan Manshadi 7 & Fatemeh Ochi 7 & Shabnam Saedi 7 & Zeinab Khodaparast 9 & Neda Shafiabadi Hassani 10 & Mehdi Azimzadeh 11 & Mostafa Qorbani 11,12 Received: 18 August 2020 / Accepted: 23 September 2020 # Springer Nature Switzerland AG 2020
Abstract Purpose Diabetic’s patients are supposed to experience higher rates of COVID-19 related poor outcomes. We aimed to determine factors predicting poor outcomes in hospitalized diabetic patients with COVID-19. Methods This retrospective cohort study included all adult diabetic patients with radiological or laboratory confirmed COVID19 who hospitalized between 20 February 2020 and 27 April 2020 in Alborz province, Iran. Data on demographic, medical history, and laboratory test at presentation were obtained from electronic medical records. Diagnosis of diabetes mellitus was selfreported. Comorbidities including cancer, rheumatism, immunodeficiency, or chronic diseases of respiratory, liver, and blood were classified as “other comorbidities” due to low frequency. The assessed poor outcomes were in-hospital mortality, need to ICU care, and receiving invasive mechanical ventilation. Self-reported. Multivariate logistic regression models were fitted to quantify the predictors of in-hospital mortality from COVID-19 in patients with DM. Results Of 455 included patients, 98(21.5%) received ICU care, 65(14.3%) required invasive mechanical ventilation, and 79 (17.4%) dead. In the multivariate model, significant predictors of “death of COVID-19” were age 65 years or older (OR (95% CI): 2.0 (1.16–3.44), chronic kidney disease (CKD) (2.05 (1.16–3.62), presence of “other comorbidities” (2.20 (1.04–4.63)), neutrophil count ≥8.0 × 109/L)6.62 (3.73–11.7 ((, Hb level < 12.5 g/dl (2.05 (1.13–3.72) (, and creatinine level ≥ 1.36 mg/dl (3.10 (1.38–6.98)). (All p –values
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