First month of the epidemic caused by COVID-19 in Italy: current status and real-time outbreak development forecast

  • PDF / 1,329,845 Bytes
  • 7 Pages / 595.276 x 790.866 pts Page_size
  • 6 Downloads / 190 Views

DOWNLOAD

REPORT


(2020) 5:43

Global Health Research and Policy

RESEARCH

Open Access

First month of the epidemic caused by COVID-19 in Italy: current status and realtime outbreak development forecast Rosario Megna

Abstract Background: The first outbreak of COVID-19 in Italy occurred during the second half of February 2020 in some areas in the North of the country. Due to the high contagiousness of the infection, further spread by asymptomatic people, Italy has become in a few weeks the country with the greatest number of infected people in the world. The large number of severe cases among infected people in Italy led to the hospitalization of thousands of patients, with a heavy burden on the National Health Service. Methods: We analyzed data provided daily by Italian Authorities for the period from 24 February 2020 to 30 March 2020. Considering such information, we developed a forecast model in real-time, based on the cumulative loglogistic distribution. Results: A total of 101,739 infected individuals were confirmed until 30 March 2020, of which 14,620 recovered or discharged, and 11,591 deaths. Until the same date patients quarantined at home were 43,752, whereas hospitalized patients were 31,776, of which 3981 in intensive care. The active cases (i.e. the number of patients not yet recovered until that date) were 75,528. The forecast model estimated a number of infected persons for Italy of 234,000 about, and a duration of the epidemic of approximately 4 months. Conclusions: One month after the first outbreaks there seemed to be the first signs of a decrease in the number of infections, showing that we could be now facing the descending phase of the epidemic. The forecast obtained thanks to our model could be used by decision-makers to implement coordinative and collaborative efforts in order to control the epidemic. The pandemic due to novel Coronavirus must be a warning for all countries worldwide, regarding a rapid and complete dissemination of information, surveillance, health organization, and cooperation among the states. Keywords: COVID-19, SARS-CoV-2, Outbreak, Forecast model, Forecast in real-time, Epidemiology

Introduction The outbreak of the novel Coronavirus called COVID19 (or SARS-CoV-2), which had the first diagnosed cases at the end of December 2019 in the Hubei Province, China [1], is having a dramatic global evolution, and was recently classified as a pandemic by the World Health Organization (WHO) on 11 March 2020 [2]. The Correspondence: [email protected] Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy

disease, which can be diagnosed through the use of a nasopharyngeal swab, under the most severe forms can lead to bilateral pneumonia [3] which can be lethal especially in elderly patients with comorbidities [4]. The initial detected outbreaks of COVID-19 in Italy occurred during the second half of February 2020 in some areas in the North of the country. First cases were diagnosed in southern Lombardy on February 21, on the border of the Veneto and Emilia Romagn