Genomic Architecture of Schizophrenia Across Diverse Genetic Isolates
This book presents a long-term study in genetic isolates of indigenous small ethnics of Dagestan, located in the North-East part of Caucasus in Russia. Dagestan is characterized by extreme cultural and linguistic differences in a small geographic area and
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omic Architecture of Schizophrenia Across Diverse Genetic Isolates A Study of Dagestan Populations
Genomic Architecture of Schizophrenia Across Diverse Genetic Isolates
Kazima Bulayeva • Oleg Bulayev • Stephen Glatt
Genomic Architecture of Schizophrenia Across Diverse Genetic Isolates A Study of Dagestan Populations
Kazima Bulayeva Russian Academy of Sciences Moscow, Russia
Oleg Bulayev Russian Academy of Sciences Moscow, Russia
Stephen Glatt Department of Psychiatry and Behavioral Sciences SUNY Upstate Medical University Syracuse, New York USA
ISBN 978-3-319-31962-9 ISBN 978-3-319-31964-3 DOI 10.1007/978-3-319-31964-3
(eBook)
Library of Congress Control Number: 2016939944 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
One of remote highland genetic isolate where we had our study
Foreword
Psychiatric disorders are among the world’s most complex and least understood ailments; yet, relative to other medical disorders, they cause a disproportionate share of suffering. The authors of this volume, Dr. Kazima Bulayeva and her son, Dr. Oleg Bulayev, have dedicated not just their scientific careers, but their lives, to combatting these disorders by increasing our understanding of their causes. Their work is the true embodiment of genetic epidemiology, defined by Newton Morton as “a science which deals with the etiology, distribution, and control of disease in groups of relatives and with inherited causes of disease in populations.”1 This volume represents a fitting compilation of decades of labor, a true labor of love that has persevered despite many obstacles, from the financial to the political, to the physical challenges of navigating the mountainous terrain of the Caucasus, to the social and cultural difficulties of developing and nurturing deep interpersona
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