Hematological Diagnostic Markers of Acute Appendicitis in Children
- PDF / 1,033,067 Bytes
- 10 Pages / 595.276 x 793.701 pts Page_size
- 57 Downloads / 205 Views
Hellenic Journal of Surgery (2018) 90:3, 127-136
Hematological Diagnostic Markers of Acute Appendicitis in Children Kostakis ID1, Angelidou Maria2, Kambouri Katerina2, Gardikis S2, Cholidou G Kyriaki2, Gioka Theodora3, Vaos G2,4
Abstract Background: White blood cell (WBC) and platelet indices are useful biomarkers in many inflammatory diseases. A study was made of possible WBC and platelet indices in children with acute appendicitis. Methods: We reviewed the results of the complete blood count tests made on admission of 150 children with acute appendicitis (94 boys, 56 girls) and those of 74 healthy children (46 boys, 28 girls). We compared the WBC and platelet indices between the children with acute appendicitis and healthy children and between the complicated and uncomplicated cases of appendicitis. Results: The children with acute appendicitis had higher WBC, neutrophil count, neutrophil percentage and neutrophil/lymphocyte ratio and lower lymphocyte count and lymphocyte percentage than the healthy children. Cases of appendicitis with complications had lower lymphocyte count, lymphocyte percentage and higher neutrophil to lymphocyte ratio than those without complications. In girls WBC, neutrophil count and neutrophil percentage were higher in complicated acute appendicitis. WBC, neutrophil count, neutrophil percentage, lymphocyte percentage and a neutrophil/lymphocyte ratio >2.5 were accurate markers for acute appendicitis in children, but not for detecting complicated cases. Girls with acute appendicitis had lower platelet distribution width than healthy girls, with high sensitivity and positive predictive value at platelet distribution width 9,900/μl [AUC: 0.925, 95% CI: 0.89-0.959, SE: 0.018, p6,700/μl [AUC: 0.933, 95% CI: 0.9010.965, SE: 0.016, p65% [AUC: 0.913, 95% CI: 0.8730.953, SE: 0.02, p
Data Loading...
