Herbal medicines
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Abdominal pain following use of an amfetaminecontaining supplement: case report A 25-year-old obese woman developed abdominal pain during treatment with a herbal weight-loss supplement containing amfetamine. The woman presented to an emergency department with a 2-week history of persistent and increasingly severe dull midgastric abdominal pain and a 1-day history of nausea and vomiting. She had been taking a Brazilian weight-loss supplement [Emagrece Sim; dosage and duration of treatment not clearly stated]; due to its high cost for a 1-month supply, she had discontinued the supplement 2 weeks before. She also reported that she experienced palpitations and tremor after taking the supplement. Over the previous 2 weeks, she had been evaluated as an outpatient and first received ranitidine and then pantoprazole for suspected gastro-oesophagal reflux syndrome, without relief of her symptoms. On presentation to the emergency department, she had a HR of 88 beats/min and diffuse, mild abdominal tenderness and hypoactive bowel sounds. She was admitted to hospital. Urinary toxicology was positive for amfetamine. Further investigations of the weightloss supplement revealed the diet capsule contained an amfetamine derivative. The woman received metoclopramide, pantoprazole and paracetamol [acetaminophen]. Her symptoms subsided and she was discharged after 3 days. She was pain-free at followup 1 week later, and metoclopramide was stopped. At 3-month follow-up, she was healthy and pain free. Nguyen MH, et al. Amphetamine lacing of an internet-marketed neutraceutical. 801060718 Mayo Clinic Proceedings 81: 1627-1629, No. 12, Dec 2006 - USA
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Reactions 27 Jan 2007 No. 1136
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