Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates

This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases. New methods in proteomics, mass spect

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Michael Pugia Editor

Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates

Progress in Inflammation Research Series Editors Michael J. Parnham Fraunhofer IME & Goethe University Frankfurt am Main, Germany Achim Schmidtko Witten, Germany

The last few years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has not only provided multiple targets for potential anti-inflammatory and immunomodulatory therapy, but has also revealed the underlying inflammatory pathology of many diseases. This monograph series provides up-to-date information on the latest developments in the pathology, mechanisms and therapy of inflammatory disease. Areas covered include: vascular responses, skin inflammation, pain, neuroinflammation, arthritis cartilage and bone, airways inflammation and asthma, allergy, cytokines and inflammatory mediators, cell signalling, and recent advances in drug therapy. Each volume is edited by acknowledged experts providing succinct overviews on specific topics intended to inform and explain. The series is of interest to academic and industrial biomedical researchers, drug development personnel and rheumatologists, allergists, pathologists, dermatologists and other clinicians requiring regular scientific updates. More information about this series at http://www.springer.com/series/4983

Michael Pugia Editor

Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates

Editor Michael Pugia Strategic Innovation Siemens Healthcare Diagnostics Elkhart, IN USA

Additional material to this book can be downloaded from http://extras.springer.com Progress in Inflammation Research ISBN 978-3-319-21926-4 ISBN 978-3-319-21927-1 DOI 10.1007/978-3-319-21927-1

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Library of Congress Control Number: 2015952543 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have b