Intracellular turnover and cardiac hypertrophy
Ultrastructural evidence is presented that intracellular autophagic degradation of cytoplasmic constituents is reduced during perssure induced hypertropy of left ventricular myocardium after supravalvular aortic constriction in rats. This anti-catabolic r
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Supplement to Basic Research in Cardiology, Vol. 81 Suppl. 1 (1986) Editors: R. Jacob (Tiibingen) Th. Kenner (Graz) and W. Schaper (Bad Nauheim)
R. Jacob (ed.)
Controversial issues in cardiac pathophysiology Erwin Riesch Symposium, July 12/13, 1985
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Springer-Verlag Berlin Heidelberg GmbH
CIP-Kurztitelaufnahme der Deutschen Bibliothek
Cootroversial issues io cardiac pathophysiology I Erwin Riesch Symposium,July 12/13,1985. R.Jacob (ed.). (Supplement to "Basic research in cardiology" ; VoI81,1) ISBN 978-3-662-11376-9 ISBN 978-3-662-11374-5 (eBook) DOI 10.1007/978-3-662-11374-5 NE: Jacob, Ruthard [Hrsg.]; Erwin-Riesch-Symposium < 1985, Starzach> ; Basic research in cardiology I Supplement Indexed in Current Contents Basic Res. Cardiol. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Unter § 54 of the German Copyright law, where copies are made for other than private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement with the publisher. Copyright © 1986 by Springer-Verlag Berlin Heidelberg Originally published by Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt in 1986 Softcover reprint of the hardcover 1st edition 1986 Copy editing: Cynthia Feast - Production: Heinz J. Schafer - Medical editorial: Juliane K. Weller The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
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Foreword The past years have witnessed considerable progress in the field of fundamental research in cardiology. Nevertheless, numerous problems and controversial concepts remain. Some of these controversies concern relatively simple issues, e. g. the question of the extent to which a common length-tension or pressure-volume relationship exists independent of type of contraction and preload. The present volume is a compendium of an Erwin Riesch symposium held July 12-13,1985, with the aim of critically analysing generally accepted concepts and theories as well as current trends in cardiology. In common with previous Erwin Riesch symposia, priority was given to issues concerning chronic reactions of the heart, although basic principles of normal myocardial contraction and ventricular dynamics as well as clinical aspects were also discussed. We are greatly indebted to the Erwin Riesch-Stiftung for the invaluable generosity which enabled us to hold the symposium. R.Jacob
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Contents Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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I. Contractile elementary processes: Cross-bridge theory and excitation-contraction coupling The cross-bridge cycle in muscle. Mechanical, biochemical, and structural studies on single skinned rabbit psoas fibers to charac
