Liver Anesthesiology and Critical Care Medicine

Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and

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Liver Anesthesiology and Critical Care Medicine

Second Edition

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Liver Anesthesiology and Critical Care Medicine

Gebhard Wagener Editor

Liver Anesthesiology and Critical Care Medicine Second Edition

Editor Gebhard Wagener Department of Anesthesiology, Columbia University Medical Center New York, NY USA

ISBN 978-3-319-64297-0    ISBN 978-3-319-64298-7 (eBook) https://doi.org/10.1007/978-3-319-64298-7 Library of Congress Control Number: 2018935600 © Springer International Publishing AG, part of Springer Nature 2012, 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To Laurie, Ben, and Anna, who allow me to enjoy life and work, and to my parents, who contributed so much to who I am.

Foreword to the First Edition

Liver transplantation has made remarkable progress in the 48 years since the first human liver transplant, and especially in the last 30 years, since the introduction of cyclosporine made long-term survival after liver transplantation feasible. A procedure that was initially untested and experimental became routine and is now the accepted treatment for end-stage liver disease in many parts of the world. About 6000 liver transplants are done in the United States every year, and graft and patient survival is excellent. We are able to administer transplants to children, do living related and split liver transplants, and only the shortage of organs limits the expansion of our field. This progress is not only due to advances in immunosuppression, surgical techniques, or organ preservation but also due to improvements in anesthetic techniques. Anesthesia care initially provided by few experts in a small number of center