Mediastinal Lesions Diagnostic Pearls for Interpretation of Small Bi
This book addresses the current concepts in tissue acquisition, diagnosis, and classification of mediastinal lesions in small biopsies including cytology. Examples of mediastinal diseases that are either more common, more challenging to diagnose, or have
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Mediastinal Lesions
Diagnostic Pearls for Interpretation of Small Biopsies and Cytology
123
Mediastinal Lesions
Anja C. Roden Andre L. Moreira •
Editors
Mediastinal Lesions Diagnostic Pearls for Interpretation of Small Biopsies and Cytology
123
Editors Anja C. Roden Department of Pathology Mayo Clinic School of Medicine Rochester, MN USA
ISBN 978-3-319-48377-1 DOI 10.1007/978-3-319-48379-5
Andre L. Moreira Department of Pathology New York University Langone Medical Center New York, NY USA
ISBN 978-3-319-48379-5
(eBook)
Library of Congress Control Number: 2016963167 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Mediastinal tumors are rare. Because of the paucity of these lesions, the experience of the practicing pathologist with biopsies from mediastinal lesions might be limited. Furthermore, mediastinal lesions are commonly biopsied because treatment differs based on diagnosis, and a surgical resection may not be performed or only after neoadjuvant therapy. Although the biopsies are primarily from malignancies, other lesions such as sclerosing mediastinitis or IgG4-related disease might also be encountered and are equally challenging. This book will focus on common mediastinal lesions and will also highlight some uncommon entities that are important because they might require different treatment modalities. We will highlight morphologic, immunophenotypic, and molecular features that can help to distinguish the disease entities in the mediastinum. Furthermore, the book will provide an overview of surgical procedures and challenges pertinent to mediastinal lesions. We also adde
