Membrane Potential Imaging in the Nervous System and Heart

This volume discusses membrane potential imaging in the nervous system and in the heart and modern optical recording technology. Additionally, it covers organic and genetically-encoded voltage-sensitive dyes; membrane potential imaging from individual neu

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Marco Canepari Dejan Zecevic Olivier Bernus Editors

Membrane Potential Imaging in the Nervous System and Heart

Advances in Experimental Medicine and Biology

Volume 859 Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy

More information about this series at http://www.springer.com/series/5584

Marco Canepari • Dejan Zecevic Olivier Bernus Editors

Membrane Potential Imaging in the Nervous System and Heart

Editors Marco Canepari Laboratoire Interdisciplinaire de Physique Grenoble, France

Dejan Zecevic Department of Cellular and Molecular Physiology Yale University School of Medicine New Haven, CT, USA

Olivier Bernus L’Institut de rythmologie et mode´lisation cardiaque LIRYC Universite´ de Bordeaux Bordeaux, France

ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-319-17640-6 ISBN 978-3-319-17641-3 (eBook) DOI 10.1007/978-3-319-17641-3 Library of Congress Control Number: 2015945022 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Preface

This book is a new edition of a previously published manual entitled Membrane Potential Imaging in the Nervous System: Methods and Applications. A significant advance in this new version is the broadening of the subject to include optical techniques for recording electrical activity of the heart in addition to the nervous system. Development of optical biotechnologies gives scientists the ability to probe more deeply into the functions of the nervous system and the heart. One of the most significant developments since