Molecular Pathology of Nervous System Tumors Biological Stratificati
This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapies. Special emphasis is given to already established and
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Matthias A. Karajannis David Zagzag Editors
Molecular Pathology of Nervous System Tumors Biological Stratification and Targeted Therapies
MOLECULAR PATHOLOGY LIBRARY Philip T. Cagle, MD, Series Editor
For further volumes: http://www.springer.com/series/7723
Matthias A. Karajannis • David Zagzag Editors
Molecular Pathology of Nervous System Tumors Biological Stratification and Targeted Therapies
Editors Matthias A. Karajannis Associate Professor of Pediatrics and Otolaryngology NYU Langone Medical Center New York, NY, USA
David Zagzag Professor of Pathology and Neurosurgery NYU Langone Medical Center New York, NY, USA
ISSN 1935-987X ISSN 1935-9888 (electronic) ISBN 978-1-4939-1829-4 ISBN 978-1-4939-1830-0 (eBook) DOI 10.1007/978-1-4939-1830-0 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014955157 © Springer Science+Business Media New York 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
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Foreword
It is difficult to believe that in the space of my career so much progress has been made in the classification and treatment of CNS tumors. Beginning in an era when with diagnoses were determined almost solely by light microscopy of H&Estained sections, and t
