Nanoparticles in Biomedical Imaging Emerging Technologies and Applic
About the Series: Fundamental Biomedical Technologies features titles in multidisciplinary, technology-driven areas, providing the foundations for breakthrough advances in medicine and biology. The term technology refers, in a vigorously unrestrictive sen
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FUNDAMENTAL BIOMEDICAL TECHNOLOGIES Series Editor: Mauro Ferrari, Ph.D. Houston, TX. Volume 1: Martin, Donald. Nanobiotechnology of Biomimetic Membranes. 978-0-387-37738-4. 2006 Volume 2: Cristini, V., M. Ferrari, and P. Decuzzi. Nanoparticulate Delivery to Cancerous Lesions. 978-0-387-29085-0. Forthcoming Volume 3: Bulte, J.W., and Mike Modo. Nanoparticles in Biomedical Imaging. 978-0-387-72026-5. 2007
Nanoparticles in Biomedical Imaging Emerging Technologies and Applications Edited by
Jeff W.M. Bulte The Johns Hopkins University School of Medicine Baltimore, USA and
Michel M.J. Modo Institute of Psychiatry, King’s College London London, United Kingdom
Jeff W.M. Bulte The Johns Hopkins University School of Medicine Department of Radiology 720 Rutland Avenue Baltimore, 21205 [email protected]
Michel M.J. Modo Institute of Psychiatry King’s College London Center for the Cellular Basis of Behaviour 125 Coldharbour Lane, London SE5 9NU United Kingdom [email protected]
Library of Congress Control Number: 2007926807
ISBN 978-0-387-72026-5
e-ISBN 978-0-387-72027-2
Printed on acid-free paper. © 2008 Springer Science+Business Media, LLC All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. 987654321 springer.com
Contents
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix List of Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1.
Introduction: The Emergence of Nanoparticles as Imaging Platform in Biomedicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Jeff. W.M. Bulte and Michel M.J. Modo
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Part 1 (Para)magnetic Nanoparticles: Applications in Magnetic Resonance Imaging 2.
MR Lymphangiography Using Nano-Sized Paramagnetic Contrast Agents with Dendrimer Cores . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Hisataka Kobayashi
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3.
Use of USPIOs for Clinical Lymph Node Imaging . . . . . . . . . . . . . . . . . . 25 Jelle O. Barentsz and Paris P. Tekkis
4.
Use of SPIOs for Clinical Liver Imaging . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Akihiro Tanimoto
5.
The Emerging Role of USPIOs for MR Imaging of Atherosclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
