Neuroblastoma Clinical and Surgical Management

This book addresses neuroblastoma, a type of embryonic tumor derived from neural crest cells and one of the most frequent extra-cranial solid tumors in children. However, the term also describes a heterogeneous group of tumors, the prognosis of which can

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Neuroblastoma

Sabine Sarnacki  •  Luca Pio Editors

Neuroblastoma Clinical and Surgical Management

Editors Sabine Sarnacki Department of Pediatric Surgery Necker - Enfants Malades Hospital Assistance Publique Hopitaux de Paris University of Paris Paris France

Luca Pio Department of Pediatric Surgery Necker - Enfants Malades Hospital Assistance Publique Hopitaux de Paris University of Paris Paris France

ISBN 978-3-030-18395-0    ISBN 978-3-030-18396-7 (eBook) https://doi.org/10.1007/978-3-030-18396-7 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Foreword

Sabine Sarnacki and Luca Pio have created a comprehensive text on neuroblastoma. This is a timely submission. The roster of authors are all international experts on the diagnosis and management of neuroblastoma. Drs. Sarnacki and Pio have compiled a text that provides information extending from the epidemiology of this disease to its imaging and, most importantly, the clinical management and surgery. This text will provide the reader a single source of the most current knowledge on all aspects of neuroblastoma. They are to be congratulated for this singular effort providing us a veritable wealth of information on neuroblastoma. I believe it will serve as an invaluable reference text for readers of all levels.

Robert C. Shamberger Surgery, Boston Children’s Hospital Harvard Medical School Harvard, MA, USA Robert E. Gross Professor of Surgery Harvard Medical School Harvard, MA, USA Chief of Surgery Boston Children’s Hospital Boston, MA, USA

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Contents

Part I Epidemiology, Biology and Pathology Assessment 1 Epidemiology�����������������������������������������������������������������