Nitric Oxide and Inflammation
Literally thousands of papers have been published on nitric oxide over the past ten years. But there is no single monograph available that has previously attempted to summarize the important features of the roles of nitric oxide in inflammation. The volum
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Series Editor Prof. Dr. Michael J. Parnham PLIVA Research Institute Prilaz baruna Filipovica 25 10000 Zagreb Croatia
Forthcoming titles: Neuroinflammatory Mechanisms in Alzheimer's Disease, J. Rogers (Editor), 2001 Mechanisms and Mediators of Neuropathic Pain, A.B. Malmberg, S.R. Chaplan (Editors), 2001 Disease-modifying Therapy in Vasculitides, C.G.M. Kallenberg, J.W. Cohen Tervaert (Editors), 2001 Inflammation and Stroke, G. Feuerstein (Editor), 2001 NMD A Antagonists as Potential Analgesic Drugs, R.G. Hill, D.J.S. Sirinathsinghji (Editors), 2001 (Already published titles see last page.)
Nitric Oxide and Inflammation
Daniela Salvemini Timothy R. Billiar Yoram Vodovotz Editors
Springer Basel A G
Editors Daniela Salvemini, Ph.D. MetaPhore Pharmaceuticals 3655 Vista Avenue St. Louis, M O 63110 USA
Timothy R. Billiar, M.D. A1010 Presbyterian University Hospital Department of Surgery 200 Lothrop Street Pittsburgh, PA 15213 USA
Yoram Vodovotz, Ph.D. University of Pittsburgh Department of Surgery UPMC Montefiore NW 653 3459 Fifth Avenue Pittsburgh, PA 15213 USA A CIP catalogue record for this book is available from the Library of Congress, Washington D.C., USA
Deutsche Bibliothek Cataloging-in-Publication Data Nitric oxide and inflammation / Daniela Salvemini, Timothy R. Billiar, Yoram Vodovotz eds.. - Basel ; Boston ; Berlin : Birkhäuser, 2001 (Progress in inflammation research) ISBN 978-3-0348-9488-3 ISBN 978-3-0348-8241-5 (eBook) DOI 10.1007/978-3-0348-8241-5
The publisher and editor can give no guarantee for the information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks etc. in this publication, even if not identified as such, does not imply that they are exempt from the relevant protective laws and regulations or free for general use.
ISBN 978-3-0348-9488-3 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright owner must be obtained. © 2001 Springer Basel AG Originally published by Birkhäuser Verlag in 2001 Softcover reprint of the hardcover 1st edition 2001 Printed on acid-free paper produced from chlorine-free pulp. TCF Cover design: Markus Etterich, Basel Cover illustration: Immunohistochemical analysis for iNOS in lungs collected 4 h following the intrapleural injection of carrageenan in rats. Using a specific anti-iNOS antibody positive brown staining was found localised in the epithelial cell as well as in inflammatory cells. The original magnification is 150x. With the friendly permission of Daniela Salvemini. ISBN 978-3-0348-9488-3 987654321
Contents
List of contributors ............................................................... vii Preface .
