Portal inflammation predicts renal dysfunction in patients with nonalcoholic fatty liver disease

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ORIGINAL ARTICLE

Portal inflammation predicts renal dysfunction in patients with nonalcoholic fatty liver disease Jung Nam An1 · Sae Kyung Joo2 · Bo Kyung Koo3 · Jung Ho Kim4 · Sohee Oh5 · Won Kim2  Received: 16 February 2020 / Accepted: 6 June 2020 © Asian Pacific Association for the Study of the Liver 2020

Abstract Background  The association between nonalcoholic fatty liver disease (NAFLD) and renal function changes remains inconclusive. We explored whether the histological severity of NAFLD is associated with early deterioration of renal function. Methods  Patients with biopsy-proven NAFLD were prospectively followed for renal function monitoring. A renal outcome was defined as a ≥ 50% increase in serum creatinine, a