Principles of bone and tissue banking in Saudi Arabia: 10-year experience report
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Principles of bone and tissue banking in Saudi Arabia: 10-year experience report Imran Ilyas . Anwar M. Al-Rabiah . Thamer S. Alhussainan . Husam A. Alrumaih . Abdulelah B. Fallatah . Shuruq A. Alsakran . Omar A. Al-Mohrej
Received: 29 June 2020 / Accepted: 25 September 2020 Ó Springer Nature B.V. 2020
Abstract Background The role of bone and tissue banking is well known to meet the ever-growing need of bone and soft tissue allografts. Strict guidelines have been established to ensure high standard and minimize complications related to bone transplantation. Methods The Bone Bank in King Faisal Specialist Hospital and Research Centre (KFSH&RC), affiliated with the Saudi Council of Organ Transplantation, was inaugurated in 2010, and it has since been an integral part of the KFSH&RC organ retrieval team. The bank has a very strict regulations which were described. Results Between January 2010 and January 2020, there were 143 multi-organ donors (mean age: 36 years, range: 24–55 years). The total number of allografts used was 2191 which were utilized in 1047 patients.
I. Ilyas A. M. Al-Rabiah T. S. Alhussainan H. A. Alrumaih O. A. Al-Mohrej (&) Department of Orthopedics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia e-mail: [email protected] I. Ilyas A. B. Fallatah Bone Bank, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia S. A. Alsakran Research Unit, Department of Orthopedics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
Conclusions In this paper, we present our 10-year experience of administrative structure, donor and recipient testing protocols, allograft retrieval, processing procedures, and the internal audit safety arrangements. The utilization of allografts in various pathologies such as revision joint replacement, spine surgery, and tumor surgery is discussed with our results over a 10-year period. Keywords Bone bank Saudi Arabia Experience Outcomes Orthopedic surgery Abbreviations KFSH&RC Faisal Specialist Hospital and Research Center KFBB King Faisal Bone Bank AATB The American Association of Tissue Banks SCOT Saudi Council of Organ Transplantation ORs Operating rooms CBC Complete blood count HBV Hepatitis B virus HBsAg HBV surface antigen HBcAb HBV core antibody HBsAb HBV surface antibody HCV Hepatitis C RPR Rapid plasma regain TPHA Treponema pallidum hemagglutination assay
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Cell Tissue Bank
EBV HIV PCR ELISA DDH NHDP
Epstein–Barr virus Human immunodeficiency virus Polymerase chain reaction Enzyme-linked immunosorbent assay Developmental dysplasia of the hip National Hip Dysplasia Program
(KFSH&RC), a tertiary care center providing service for all complex cases around the country.
Methods Administrative structure
Introduction The demand for bone allograft has risen steeply over the last several decades owing to bone defects from trauma (Al-Mohrej and Al-Dera 2015), infections (Friedlaender 1987), resection of bone tumors (Mankin et al. 1996), a
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