Prognostic impact of preoperative renal function in patients treated with radical cystectomy: a multi-institutional retr
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ORIGINAL ARTICLE
Prognostic impact of preoperative renal function in patients treated with radical cystectomy: a multi‑institutional retrospective study Dai Koguchi1,2 · Kazumasa Matsumoto1 · Masaomi Ikeda3 · Yoshinori Taoka2 · Takahiro Hirayama1 · Yasukiyo Murakami1 · Takuji Utsunomiya4 · Daisuke Matsuda5 · Norihiko Okuno6 · Akira Irie3 · Masatsugu Iwamura1 Received: 8 December 2019 / Accepted: 23 June 2020 © Japan Society of Clinical Oncology 2020
Abstract Background Little data on the preoperative prognostic factors in radical cystectomy (RC) patients have made it difficult to choose the appropriate type of urothelial diversion (UD). This study aimed to investigate the prognostic role of UD, with a subgroup analysis of that of preoperative renal function. Methods From 1990 to 2015, 279 patients underwent RC for bladder cancer at six hospitals affiliated with Kitasato University in Japan. All patients were divided into three groups: cutaneous ureterostomy (CU; n = 54), ileal conduit (IC; n = 139), and orthotopic neobladder (NB; n = 86). Patients were also stratified into three groups based on preoperative estimated glomerular filtration rate (eGFR) (mL/min/1.73 m2): normal eGFR (> 60 mL/min/1.73 m2; n = 149), moderately reduced eGFR (45–60 mL/min/1.73 m2; n = 66), and severely reduced eGFR ( 60 mL/min/1.73 m2; n = 149), moderately reduced eGFR (45–60 mL/min/1.73 m2; n = 66), and severely reduced eGFR (
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