+Psychometric evaluation of the MacDQoL individualised measure of the impact of macular degeneration on quality of life
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+Psychometric evaluation of the MacDQoL individualised measure of the impact of macular degeneration on quality of life Jan Mitchell*1, James S Wolffsohn2, Alison Woodcock1, Stephen J Anderson2, Carolyn V McMillan1, Timothy ffytche3, Martin Rubinstein4, Winfried Amoaku4 and Clare Bradley1 Address: 1Department of Psychology, Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK, 2Neurosciences Research Institute, Aston University, Birmingham, B4 7ET, UK, 3Hospital for Tropical Diseases, Capper Street, London WC1E 6AU, UK and 4Eye Department, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK Email: Jan Mitchell* - [email protected]; James S Wolffsohn - [email protected]; Alison Woodcock - [email protected]; Stephen J Anderson - [email protected]; Carolyn V McMillan - [email protected]; Timothy ffytche - [email protected]; Martin Rubinstein - [email protected]; Winfried Amoaku - [email protected]; Clare Bradley - [email protected] * Corresponding author
Published: 14 April 2005 Health and Quality of Life Outcomes 2005, 3:25
doi:10.1186/1477-7525-3-25
Received: 06 October 2004 Accepted: 14 April 2005
This article is available from: http://www.hqlo.com/content/3/1/25 © 2005 Mitchell et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: The MacDQoL is an individualised measure of the impact of macular degeneration (MD) on quality of life (QoL). There is preliminary evidence of its psychometric properties and sensitivity to severity of MD. The aim of this study was to carry out further psychometric evaluation with a larger sample and investigate the measure's sensitivity to MD severity. Methods: Patients with MD (n = 156: 99 women, 57 men, mean age 79 ± 13 years), recruited from eye clinics (one NHS, one private) completed the MacDQoL by telephone interview and later underwent a clinic vision assessment including near and distance visual acuity (VA), comfortable near VA, contrast sensitivity, colour recognition, recovery from glare and presence or absence of distortion or scotoma in the central 10° of the visual field. Results: The completion rate for the MacDQoL items was 99.8%. Of the 26 items, three were dropped from the measure due to redundancy. A fourth was retained in the questionnaire but excluded when computing the scale score. Principal components analysis and Cronbach's alpha (0.944) supported combining the remaining 22 items in a single scale. Lower MacDQoL scores, indicating more negative impact of MD on QoL, were associated with poorer distance VA (better eye r = -0.431 p < 0.001; worse eye r = -0.350 p < 0.001; binocular vision r = -0.419 p < 0.001) and near VA (better eye r = -0.326 p < 0.001; worse eye r = -0.226 p < 0.
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