Quality of Life and Costs in Atopic Dermatitis
Patients with atopic dermatitis ( AD ) experience considerable burden due to the disease. This burden is multidimensional and impacts health-related quality of life (HRQOL), finances and treatment choices. A lower quality of life ( QOL ) results from decr
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Introduction – Atopic Dermatitis and Health Related Quality of Life (HRQOL) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2164
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HRQOL Instruments Used in AD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2165
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Impact of AD on Patient HRQOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2171
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Impact of AD on Caregiver and Family HRQOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2171
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Effect of Treatment on HRQOL in AD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2173
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Cost Burden and Cost-Effectiveness Analyses Associated with Atopic Dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2173
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Therapy-Specific Cost and Cost-Effectiveness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2174 Topical Corticosteroids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2174 Topical Immunomodulators . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2175 Non-Corticosteroids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2180 Summary Points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2180
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Springer Science+Business Media LLC 2010 (USA)
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Quality of Life and Costs in Atopic Dermatitis
Abstract: Patients with atopic dermatitis (> AD) experience considerable burden due to the disease. This burden is multidimensional and impacts health-related quality of life (HRQOL), finances and treatment choices. A lower quality of life (> QOL) results from decreased social functioning, worse mental health, anxiety and stress, increased incidence of psychiatric disorders, behavioral problems and sleep loss. The burden of AD reaches beyond the patient and extends to caretakers and parents of children with AD, families of patients with AD, and partners of adults with AD. However, while AD has been shown to negatively impact HRQOL of both patients and their caregivers, there is evidence that effective treatment, specifically > immunomodulators, can significantly improve HRQOL. In addition to its considerable impact on patient QOL, the monetary burden of AD is substantial. Studies have demonstrated > direct costs ranging from US $150 to 580 per patient per year, with the range of costs being reported due to different > cost-accounting methods. Typically, outpatient visits and medications comprised the majority of direct costs and costs tended to increase with increasing severity of AD. There have been several studies comparing
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