Role of Obesity Variables in Detecting Hypertension in an Iranian Population
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ORIGINAL ARTICLE
Role of Obesity Variables in Detecting Hypertension in an Iranian Population Patricia Khashayar1,2 Bagher Larijani4
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Hamidreza Aghaei Meybodi1 • Mohsen Rezaei Hemami3
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Received: 1 May 2017 / Accepted: 6 June 2017 Ó Springer International Publishing AG 2017
Abstract Introduction As the high incidence of hypertension has been in conjunction with dramatic increase in the prevalence of obesity, many studies have suggested obesity as its underlying cause in diverse race and ethnic groups. Aim The present study was designed to quantify the relationship between obesity variables and hypertension in Iranian population. A ROC curve analysis was also used to determine an optimal BMI cutoff for obesity with the aim of representing elevated incidence of hypertension in this population. Methods The study population comprised of apparently healthy men and women who participated in the Iranian Multicentric Osteoporosis Studies (IMOS), a multi-centric crosssectional study carried out in urban areas of five great cities (Tehran, Tabriz, Mashhad, Shiraz and Bushehr). The anthropometric (weight, height, waist and hip circumferences) and blood pressure measures were reported in some 5724 subjects. The influence of these factors on systolic and diastolic blood pressure was assessed based on a list-wise method. Results There was a significant difference in the studied subjects anthropometric (weight classes (BMI), WC and
& Bagher Larijani [email protected] 1
Osteoporosis Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran
2
Center for Microsystems Technology, Imec and Ghent University, Zwijnaarde, Ghent, Belgium
3
Institute of HEHTA, University of Glasgow, Glasgow, UK
4
Endocrinology and Metabolism Research Center (EMRC), Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, 1411413137 Tehran, Iran
HC, and WHR) and blood pressure variables; age, gender and weight, however, were the only factors significantly influencing SBP and DBP. Furthermore, BMI showed a significant impact on the overall risk of developing hypertension. Conclusion General obesity rather than abdominal obesity is directly linked with higher blood pressure levels in Iranian population. Keywords Obesity Abdominal obesity Blood pressure Hypertension Systolic blood pressure Diastolic blood pressure Waist circumference Waist to hip ratio
1 Introduction Nowadays, hypertension, an accelerator of cardiovascular events and renal disorders, has become a global public health concern because of its high prevalence [1, 2]. In view of the fact that its high incidence has been in conjunction with the dramatic increase in the prevalence of obesity, many studies have suggested obesity as its underlying cause in diverse race and ethnic groups [3–5]. Although the physiopathology of obesity-related hypertension is not fully understood, renal malfunction and insulin resistance are considered as the main causes contributing to the conditio
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