The impact of wearable cardioverter-defibrillator use on long-term decision for implantation of a cardioverter-defibrill

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The impact of wearable cardioverter-defibrillator use on long-term decision for implantation of a cardioverter-defibrillator in a semirural acute care hospital Anil-Martin Sinha 1,2 & Jens Bense 1,2 & Wolfgang Hohenforst-Schmidt 1,2 Received: 2 August 2020 / Accepted: 12 October 2020 # The Author(s) 2020

Abstract Purpose Large-scale multi-center studies have reported on efficacy of the wearable cardioverter-defibrillator (WCD). However, outcomes focused on WCD patients treated at community-based acute care centers are lacking. Methods Patients with cardiomyopathy were included when left ventricular ejection fraction (LVEF) at baseline was ≤ 35%. There were 120 patients meeting the criteria who also had LVEF measured at baseline and after 90 days of WCD use. Results After 90 days of WCD use, there were 44 (37%) patients in whom LVEF improved to > 35%. Comparison of patients, by whether LVEF improved or not, indicated that median days of WCD wear and hours of daily use were similar as well as characteristics, such as gender, age, and starting LVEF; and diagnoses leading to WCD prescription were similar between groups as were symptom-based prescription of medications. At the end of WCD use, improved LVEF > 35% correlated with fewer implantable cardioverter-defibrillator (ICD) implants. There were 4 (3%) episodes of new atrial fibrillation detected during WCD use. The WCD appropriately delivered a shock to 3 (2.5%) patients with VT/VF being terminated by the first shock. All shocked patients survived for at least 24 h post-shock. Conclusions During WCD use, ischemic and non-ischemic cardiomyopathy patients manifest improved LVEF by 90 days. Long-term care decisions, such as implantation of an ICD, were influenced by LVEF improvement and occurrence of spontaneous VT/VF. The WCD protected patients from sudden cardiac death (SCD) until patient response to guideline-directed medical therapy could be determined. Keywords Arrhythmia . Cardiomyopathy . Implantable cardioverter-defibrillator . Sudden cardiac arrest . Sudden cardiac death . Wearable cardioverter-defibrillator

Abbreviations DCM Dilative cardiomyopathy ECG Electrocardiogram ESC European Society of Cardiology EMS Emergency medical services GDMT Guideline-directed medical therapy ICD Implantable cardioverter-defibrillator ICM Ischemic cardiomyopathy IQR Interquartile range

LVEF MI NICM PCI SCD VEST VF VT WCD

* Anil-Martin Sinha [email protected]

1 Introduction

1

Department of Cardiology, Sana Klinikum Hof, Eppenreuther Str. 9, 95032 Hof, Germany

2

Department of Cardiology, Teaching Hospital of the Friedrich Alexander University Erlangen/Nürnberg, Erlangen/ Nürnberg, Germany

Left ventricular ejection fraction Myocardial infarction Non-ischemic cardiomyopathy Percutaneous coronary intervention Sudden cardiac death Vest Prevention of Early Sudden Death Trial Ventricular fibrillation Ventricular tachycardia Wearable cardioverter-defibrillator

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