The Neuroscience Information Framework: A Data and Knowledge Environment for Neuroscience

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The Neuroscience Information Framework: A Data and Knowledge Environment for Neuroscience Daniel Gardner & Huda Akil & Giorgio A. Ascoli & Douglas M. Bowden & William Bug & Duncan E. Donohue & David H. Goldberg & Bernice Grafstein & Jeffrey S. Grethe & Amarnath Gupta & Maryam Halavi & David N. Kennedy & Luis Marenco & Maryann E. Martone & Perry L. Miller & Hans-Michael Müller & Adrian Robert & Gordon M. Shepherd & Paul W. Sternberg & David C. Van Essen & Robert W. Williams

Published online: 23 October 2008 # The Author(s) 2008. This article is published with open access at Springerlink.com

Abstract With support from the Institutes and Centers forming the NIH Blueprint for Neuroscience Research, we have designed and implemented a new initiative for integrating access to and use of Web-based neuroscience

D. Gardner (*) : D. H. Goldberg : B. Grafstein : A. Robert Laboratory of Neuroinformatics and Department of Physiology, Weill Medical College, Cornell University, 1300 York Avenue, New York, NY 10065, USA e-mail: [email protected]

resources: the Neuroscience Information Framework. The Framework arises from the expressed need of the neuroscience community for neuroinformatic tools and resources to aid scientific inquiry, builds upon prior development of

D. N. Kennedy Departments of Neurology and Radiology, Harvard Medical School, Boston, MA 02129, USA

H. Akil Molecular and Behavioral Neuroscience, University of Michigan, Ann Arbor, MI 48109, USA

L. Marenco : P. L. Miller : G. M. Shepherd Department of Neurobiology and Yale Center for Medical Informatics, School of Medicine, Yale University, New Haven, CT 06510, USA

G. A. Ascoli : D. E. Donohue : M. Halavi Center for Neural Informatics, Structure, and Plasticity and Molecular Neuroscience Department, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA

H.-M. Müller : P. W. Sternberg Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA

D. M. Bowden National Primate Research Center, University of Washington, Seattle, WA 98195, USA W. Bug : J. S. Grethe : M. E. Martone Department of Neurosciences, University of California, San Diego, CA 92093, USA A. Gupta San Diego Supercomputer Center, University of California, San Diego, CA 92093, USA

D. C. Van Essen Department of Anatomy and Neurobiology, School of Medicine, Washington University, St. Louis, MO 63110, USA R. W. Williams Department of Anatomy and Neurobiology and Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA

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neuroinformatics by the Human Brain Project and others, and directly derives from the Society for Neuroscience’s Neuroscience Database Gateway. Partnered with the Society, its Neuroinformatics Committee, and volunteer consultant-collaborators, our multi-site consortium has developed: (1) a comprehensive, dynamic, inventory of Web-accessible neuroscience resources, (2) an extended and integrated terminology describing resources and contents, and (3) a fr