Tumours of the Pituitary Region

Those interested in a more detailed account of the history of the development of the treatment of pituitary tumours are referred to the excellent chapter of Professor Landolt [1]. A more succinct account may be found in another chapter by Professor Takaku

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Jeremy C. Ganz

Gamma Knife Neurosurgery

SpringerWienNewYork

Dr. Jeremy C. Ganz Oysteinsgate 16 5007 Bergen Norway [email protected]

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machines or similar means, and storage in data banks. Product Liability: The publisher can give no guarantee for all the information contained in this book. The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. # Springer-Verlag/Wien 2011 Printed in Germany SpringerWienNewYork is a part of Springer Science+Business Media springer.at Typesetting: SPI, Pondicherry, India Printed on acid-free and chlorine-free bleached paper SPIN: 12791149 With 73 Figures Library of Congress Control Number: 2010935853 ISBN 978-3-7091-0342-5 e-ISBN 978-3-7091-0343-2 DOI 10.1007/978-3-7091-0343-2 SpringerWienNewYork

This book is dedicated to my wife “Annie” Gao Nan Ping. Only the wives of authors can truly understand the domestic upheaval that results from an author’s pre-occupation and obsession over his writing. Without her constant and unceasing support this book would never have been written.

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Foreword

This new addition to the plethora of literature on radiosurgery in general and Gamma Knife surgery in particular, is a massive and phenomenal accomplishment. In 1993 Doctor Ganz wrote the book “Gamma Knife Surgery – A Guide for referring physicians”. A revised edition was published again by Springer in 1997. As indicated by its title, this book was intended for the general practitioner who needed to get a fleeting understanding of Gamma Knife surgery in order to be able to make informed recommendations to his or her patients. While the book accomplished this objective it was too sketchy to become a true work of reference, for a novice in the field or even for an established practitioner of Gamma Knife surgery. All the limitations of the previous book(s) have been addressed in detail in this tome. As you read this work you will be led through every relevant aspect of the field in a most didactic and enjoyable way. Doctor Ganz, never known to be shy, doesn’t steer away from controversial issues but rather, and admirably, addresses them head on! Part I of “Gamma Knife Neurosurgery” starts with a look at the definition of radiosurgery and how this has evolved recently. The original definition of radiosurgery called for a high dose of ionizing radiation being delivered in a single session. This is how radiosurgery is administered to intracerebral targets, mostly using a stereotactic frame anchored to the skull. As the use of radiosurgery has become increasingly widespread it has also been attractive to apply it to various extracerebral targets. As a consequence fixation principles also ha