Validation of an abbreviated Treatment Satisfaction Questionnaire for Medication (TSQM-9) among patients on antihyperten
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Validation of an abbreviated Treatment Satisfaction Questionnaire for Medication (TSQM-9) among patients on antihypertensive medications Murtuza Bharmal*1, Krista Payne2, Mark J Atkinson3, MariePierre Desrosiers2, Donald E Morisky4 and Eric Gemmen1 Address: 1Quintiles Inc, Falls Church, Virginia, USA, 2United BioSource Corporation, Montreal, Canada, 3University of California, San Diego, California, USA and 4UCLA School of Public Health, Los Angeles, California, USA Email: Murtuza Bharmal* - [email protected]; Krista Payne - [email protected]; Mark J Atkinson - [email protected]; Marie-Pierre Desrosiers - [email protected]; Donald E Morisky - [email protected]; Eric Gemmen - [email protected] * Corresponding author
Published: 27 April 2009 Health and Quality of Life Outcomes 2009, 7:36
doi:10.1186/1477-7525-7-36
Received: 8 August 2008 Accepted: 27 April 2009
This article is available from: http://www.hqlo.com/content/7/1/36 © 2009 Bharmal et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: The 14-item Treatment Satisfaction Questionnaire for Medication (TSQM) Version 1.4 is a reliable and valid instrument to assess patients' satisfaction with medication, providing scores on four scales – side effects, effectiveness, convenience and global satisfaction. In naturalistic studies, administering the TSQM with the side effects domain could provoke the physician to assess the presence or absence of adverse events in a way that is clinically atypical, carrying the potential to interfere with routine medical care. As a result, an abbreviated 9-item TSQM (TSQM-9), derived from the TSQM Version 1.4 but without the five items of the side effects domain was created. In this study, an interactive voice response system (IVRS)administered TSQM-9 was psychometrically evaluated among patients taking antihypertensive medication. Methods: A total of 3,387 subjects were invited to participate in the study from an online panel who self-reported taking a prescribed antihypertensive medication. The subjects were asked to complete the IVRS-administered TSQM-9 at the start of the study, along with the modified Morisky scale, and again within 7 to 14 days. Standard psychometric analyses were conducted; including Cronbach's alpha, intraclass correlation coefficients, structural equation modeling, Spearman correlation coefficients and analysis of covariance (ANCOVA). Results: A total of 396 subjects completed all the study procedures. Approximately 50% subjects were male with a good racial/ ethnic mix: 58.3% white, 18.9% black, 17.7% Hispanic and 5.1% either Asian or other. There was evidence of construct validity of the TSQM-9 based on the structural equation modeling findings of
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