Regenerative Medicine - from Protocol to Patient 1. Biology of Tissu

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology, as well as advanced molecular and cellular techniques. This collection of volumes on Regener

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Regenerative Medicine - from Protocol to Patient 1. Biology of Tissue Regeneration Third Edition

Regenerative Medicine - from Protocol to Patient

Gustav Steinhoff Editor

Regenerative Medicine from Protocol to Patient 1.

Biology of Tissue Regeneration

Third Edition

Editor Gustav Steinhoff Department of Cardiac Surgery and Reference and Translation Center of Cardiac Stem Cell Therapy (RTC), Medical Faculty University of Rostock Rostock, Mecklenburg-Vorpomm, Germany

Edition 3: published in five separate volumes: Vol. 1: 978-3-319-27581-9 Vol. 2: 978-3-319-27608-3 Vol. 3: 978-3-319-28272-5 Vol. 4: 978-3-319-28291-6 Vol. 5: 978-3-319-28384-5 ISBN 978-3-319-27581-9 ISBN 978-3-319-27583-3 DOI 10.1007/978-3-319-27583-3

(eBook)

Library of Congress Control Number: 2016931901 Originally published in one volume: 1st edition: ISBN: 978-90-481-9074-4 (Print) 978-90-481-9075-1 (Online) (2011) 2nd edition: ISBN: 978-94-007-5689-2 (Print) 978-94-007-5690-8 (Online) (2013) © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland

Foreword: Regenerative Medicine: From Protocol to Patient

Third Edition The vision to unravel and develop biological healing mechanisms based on evolving molecular and cellular technologies has led to a worldwide scientific endeavour to establish regenerative medicine. This field involves interdisciplinary basic and (pre) clinical research and development on the repair, replacement, regrowth or regeneration of cells, tissues or organs in congenital or acquired diseases. Stem cell science and regenerative biology is prompting the most fascinating and controversial medical development of the twenty-first century. It can be envisaged that this development will establish completely new molecular and cellular techniques for medical diagnosis and therapy. The earl

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