Selenium Its Molecular Biology and Role in Human Health

In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field. Evidence from epidemiology and vet

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Its Molecular Biology and Role in Human Health Fourth Edition

Selenium

Dolph L. Hatfield • Ulrich Schweizer Petra A. Tsuji • Vadim N. Gladyshev Editors

Selenium Its Molecular Biology and Role in Human Health Fourth Edition

Editors Dolph L. Hatfield Mouse Cancer Genetics Program National Cancer Institute National Institutes of Health Bethesda, MD, USA Petra A. Tsuji Department of Biological Sciences Towson University Towson, MD, USA

Ulrich Schweizer Institut für Biochemie und Molekularbiologie Rheinische Friedrich-Wilhelms-Universität Bonn Bonn, Nordrhein-Westfalen, Germany Vadim N. Gladyshev Division of Genetics Department of Medicine Brigham and Women’s Hospital Harvard Medical School Boston, MA, USA

ISBN 978-3-319-41281-8 ISBN 978-3-319-41283-2 DOI 10.1007/978-3-319-41283-2

(eBook)

Library of Congress Control Number: 2016948304 © Springer Science+Business Media, LLC 2001, 2006, 2012, 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC New York

Dedication

This book is dedicated to the pioneers in the selenium field, who provided the foundation for the enormous amount of research that has occurred in recent years, bringing extraordinary insights to selenium biology and its role in health and development of humans and other mammals. The discoverer of selenium, Jöns Jacob Berzelius, a Swedish chemist, deserves special recognition as he identified this element in 1817 as a by-product of sulfuric acid production. As we are now on the verge of the 200th anniversary of the Berzelius discovery, this new edition is particularly timely. The anniversary will also be the prevailing theme of The 11th International Symposium on Selenium in Biology and Medicine and The 5th International Conference on Selenium in the Environment and Human Health, to be held in Stockholm, Sweden, in August 2017. One of the early studies that impacted how selen