Sleep, Memory and Synaptic Plasticity

Over the years there has been growing interest among the scientific community in investigating sleep and how it affects the memory and other brain functions. It is now well established that sleep helps in memory consolidation and induction of neural plast

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p, Memory and Synaptic Plasticity

Sleep, Memory and Synaptic Plasticity

Sushil K. Jha • Vibha M. Jha Editors

Sleep, Memory and Synaptic Plasticity

Editors Sushil K. Jha Sleep Research Laboratory, School of Life Sciences Jawaharlal Nehru University New Delhi, India

Vibha M. Jha Sleep Research Laboratory, School of Life Sciences Jawaharlal Nehru University New Delhi, India

ISBN 978-981-13-2813-8 ISBN 978-981-13-2814-5 https://doi.org/10.1007/978-981-13-2814-5

(eBook)

Library of Congress Control Number: 2018967722 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Each night, when I go to sleep, I die. And the next morning, when I wake up, I am reborn.

Mahatma Gandhi

A spiritual chant in Indian mythology for a good night’s sleep:

Ya Devi Sarva bhuteshu Nidra Roopen Sanstithah Namastasyai Namastasyai Namastasyai Namo Namah (O Goddess, you are omnipresent. You also exist in sleep. I bow to you.)

Preface

Most animals spend a significant amount of time in sleep, yet its core functions are mostly unknown. There is increasing evidence suggesting that sleep helps in memory consolidation and induction of neural plasticity. In several studies, it has been demonstrated that short-term deprivation of either total sleep or rapid eye movement (REM) sleep alone soon after a learning task induces memory deficit. Quantitative and qualitative changes in sleep architecture after different training tasks further suggest that discrete memory types may require a specific sleep stage(s) for optimal memory consolidation. For example, in rodents, non-REM (NREM) sleep, slowwave activity, and sleep spindle density during NREM sleep increased af