Stress, Trauma and Synaptic Plasticity

This book provides detailed insights into the cellular and molecular alterations that occur in the brain following stress and trauma. The changes to the grey matter in certain areas of the brain are similar in stressed humans and animals, with the most li

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Stress, Trauma and Synaptic Plasticity

Stress, Trauma and Synaptic Plasticity

Maxwell Bennett • Jim Lagopoulos

Stress, Trauma and Synaptic Plasticity

Maxwell Bennett The University of Sydney Brain and Mind Centre Camperdown NSW, NSW, Australia

Jim Lagopoulos Sunshine Coast Mind and Neuroscience Thompson Institute University of Sunshine Coast Birtinya, QLD, Australia

ISBN 978-3-319-91115-1 ISBN 978-3-319-91116-8 https://doi.org/10.1007/978-3-319-91116-8

(eBook)

Library of Congress Control Number: 2018962162 # Springer Nature Switzerland AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Cover illustration: Robert Klein-Boonschate, Born, Deveter, The Netherlands. Currently, Walla Walla, NSW, Australia. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

Stress and trauma bring untold suffering into the lives of individuals, whether that of a genius with depression as described in Virginia Wolf and neuropsychiatry by one of us or in retired ex-service men and women diagnosed with post-traumatic stress disorder. It is for great literary figures to illuminate the humanistic dimensions to this suffering and for neuropsychiatrists to determine what has gone awry in the brain that gives rise to it. This work is concerned with the neuroscientific perspective. Some object to the description of animal studies on stress and trauma occurring between the same covers as a description of human suffering, believing that the former denigrates those experiencing the latter. But evolution has conserved many of the neural networks that support our normal behaviour pertaining to fear and pain; hence it would be very foolish to abandon the study of what has gone awry in the animal brain that gives rise to, for example, anxiety behaviour. This app