Synthesis, characteristics and medical applications of plant nanomaterials
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REVIEW
Synthesis, characteristics and medical applications of plant nanomaterials Lidong Du1 · Ruoyu Zhang2 · Hanchao Yang4 · Shaojian Tang3 · Zhaohua Hou5 · Jinjin Jing2 · Bingjie Lin2 · Shujie Zhang2 · Zhong Lu1,4 · Peng Xue2 Received: 27 August 2020 / Accepted: 2 November 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Main conclusion The recent preparations of metal nanoparticles using plant extracts as reducing agents are summarized here. The synthesis and characterization of plant–metal nanomaterials and the progress in antibacterial and anti-inflammatory medical applications are detailed, providing a new vision for plant-based medical applications. Abstract The medical application of plant-metal nanoparticles is becoming a research hotspot. Compared with traditional preparation methods, the synthesis of plant-metal nanoparticles is less toxic and more eco-friendly, increasing application potential. Highly efficient plant-metal nanoparticles are usually smaller than 100 nm. This review describes the synthesis, characterization and bioactivities of gold- and silver-plant nanoparticles as examples and clearly explained their antibacterial and anticancer mechanisms. An analysis of actual cases shows that the synthetic method and type of plant extract affect the activities of the products.
Introduction Since the end of the twentieth century, the synthesis and use of nanoparticles (NPs) has become a hot topic of research. At the outset, NP, including those made of gold, silver, Communicated by Gerhard Leubner. Lidong Du and Ruoyu Zhang authors have contributed equally to this work. * Zhong Lu [email protected] * Peng Xue [email protected] 1
School of Clinical Medical, Weifang Medical University, Weifang 261053, People’s Republic of China
2
School of Public Health, Weifang Medical University, Weifang 261053, People’s Republic of China
3
School of Pharmacy, Weifang Medical University, Weifang 261053, People’s Republic of China
4
Affiliated Hospital of Weifang Medical University, Weifang 261053, People’s Republic of China
5
College of Food Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, People’s Republic of China
platinum, copper, zinc and their oxides, have been proven to be good bioactive materials (Mata et al. 2015; Babu and Antony 2018). NPs are some of the best candidates for replacing the conventional method of antibiotic treatment because of their strong broad-spectrum antimicrobial properties and low toxicity. The use of NPs in cancer therapy is also promising, with previous data showing that NPs can affect a variety of cancer cells. In recent decades, research on the antibacterial and anticancer properties of NPs has continued to increase, which can be proven by the large amount of related literature data. (Fig. 1a, b). As a common carrier, precious metals are widely studied, especially gold, silver and other precious metals (Thanganadar Appapalam and Panchamoorthy 2017; Veisi et al. 2018). Generally, par
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